What do systematic reviews say?

Supervised exercise therapy following vascular intervention vs vascular intervention alone

It is very uncertain whether supervised exercise therapy following vascular intervention changes mortality compared with vascular intervention alone (very low certainty).

• Effects of additional exercise therapy after a successful vascular intervention for people with symptomatic peripheral… 2024 · Cochrane Headline outcomes only
  OR 0.92 [0.42, 2]
  6 studies · 346 participants
  Very low

Anticoagulant vs placebo or no intervention

Anticoagulant showed no clear difference in overall mortality ( compared with no intervention or placebo (low certainty).

• Treatment of distal deep vein thrombosis 2020 · Cochrane Headline outcomes only
  RR 3.2 [0.13, 77.69]
  3 studies · 430 participants
  Low

Anticoagulant vs placebo or no intervention

• Treatment of distal deep vein thrombosis 2020 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 430 participants
  GRADE not reported

Berotralstat vs placebo or active control

The review found no eligible studies for this question.

• Interventions for the long‐term prevention of hereditary angioedema attacks 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

C1 esterase inhibitor vs placebo or active control

The review found no eligible studies for this question.

• Interventions for the long‐term prevention of hereditary angioedema attacks 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Plasma‐derived C1 esterase inhibitor vs placebo or active control

The review found no eligible studies for this question.

• Interventions for the long‐term prevention of hereditary angioedema attacks 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Avoralstat vs placebo

The review found no eligible studies for this question.

• Interventions for the long‐term prevention of hereditary angioedema attacks 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Nanofiltered C1 esterase inhibitor vs placebo or active control

The review found no eligible studies for this question.

• Interventions for the long‐term prevention of hereditary angioedema attacks 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Recombinant human C1 esterase inhibitor vs placebo or active control

The review found no eligible studies for this question.

• Interventions for the long‐term prevention of hereditary angioedema attacks 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Lanadelumab vs placebo or active control

The review found no eligible studies for this question.

• Interventions for the long‐term prevention of hereditary angioedema attacks 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Heparin vs pentasaccharide

• Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 198 participants
  Very low

Heparin started before vs after the surgical procedure

• Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 100 participants
  Very low

IPC plus pharmacological prophylaxis vs mechanical prophylaxis alone

• Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 150 participants
  Low

Higher‐dose heparin vs standard‐dose heparin

• Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery 2022 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 597 participants
  Low

Gait training protocol focused on impairment level vs gait training protocol focused on task level

The review found no eligible studies for this question.

• Interventions for motor rehabilitation in people with transtibial amputation due to peripheral arterial disease or… 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Low molecular weight heparin vs no prophylaxis

• Interventions for preventing venous thromboembolism in adults undergoing knee arthroscopy 2022 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 1978 participants
  GRADE not reported

Heparin vs pentasaccharide

• Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 198 participants
  Very low

Heparin started before vs after the surgical procedure

• Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 100 participants
  Very low

IPC plus pharmacological prophylaxis vs mechanical prophylaxis alone

• Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 150 participants
  Low

Higher‐dose heparin vs standard‐dose heparin

• Pharmacological interventions for preventing venous thromboembolism in people undergoing bariatric surgery 2022 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 597 participants
  Low