Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

13 questions · 15 findings · 6 reviews · Headline outcomes only

No studies found 3 · 20%GRADE not reported 0 · 0%Very low 4 · 26.7%Low 3 · 20%Moderate 4 · 26.7%High 1 · 6.7%

Aspirin vs placebo

Total mortality · adults with hypertension (patients with atrial fibrillation, congestive heart failure, pre‐eclampsia or pulmonary hypertension were…

Aspirin showed no clear difference in total mortality compared with placebo (low certainty).

1 finding from 1 review

Aspirin vs placebo

Cardiovascular mortality · adults with hypertension (patients with atrial fibrillation, congestive heart failure, pre‐eclampsia or pulmonary hypertension were…

Aspirin showed no clear difference in cardiovascular mortality compared with placebo (low certainty).

1 finding from 1 review

clopidogrel plus aspirin vs aspirin

All‐cause mortality · people with coronary disease, ischaemic cerebrovascular disease, peripheral arterial disease or at high risk of atherothrombotic disease

clopidogrel plus aspirin showed no clear difference in all‐cause mortality compared with aspirin alone (low certainty).

1 finding from 1 review

clopidogrel plus aspirin vs aspirin

Cardiovascular mortality · people with coronary disease, ischaemic cerebrovascular disease, peripheral arterial disease or at high risk of atherothrombotic disease

clopidogrel plus aspirin showed no clear difference in cardiovascular mortality compared with aspirin alone (moderate certainty).

1 finding from 1 review

Aspirin vs vitamin K antagonist (VKA)

All‐cause mortality · ambulatory patients with multiple myeloma receiving immunomodulatory agents

It is very uncertain whether aspirin (ASA) changes all‐cause mortality compared with vitamin K antagonist (VKA) (very low certainty).

2 findings from 1 review

Aspirin vs low molecular weight heparin

All‐cause mortality · ambulatory patients with multiple myeloma receiving immunomodulatory agents

It is very uncertain whether aspirin (ASA) changes all‐cause mortality compared with low molecular weight heparin (LMWH) (very low certainty).

2 findings from 1 review

Intervention not reported

Mortality · patients with venous leg ulcers

The review found no eligible studies for this question.

1 finding from 1 review