Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

5 questions · 5 findings · 3 reviews · Heart

No studies found 0 · 0%GRADE not reported 1 · 20%Very low 0 · 0%Low 3 · 60%Moderate 1 · 20%High 0 · 0%

Does treatment guided by serial BNP or NT‐proBNP monitoring improve outcomes vs treatment guided by clinical assessment alone?

Heart failure mortality · patients with heart failure

Does treatment guided by serial BNP or NT‐proBNP monitoring improve… showed no clear difference in heart failure mortality compared with treatment guided by clinical assessment alone? (low certainty).

1 finding from 1 review

clopidogrel plus aspirin vs aspirin

All‐cause mortality · people with coronary disease, ischaemic cerebrovascular disease, peripheral arterial disease or at high risk of atherothrombotic disease

clopidogrel plus aspirin showed no clear difference in all‐cause mortality compared with aspirin alone (low certainty).

1 finding from 1 review

Does treatment guided by serial BNP or NT‐proBNP monitoring improve outcomes vs treatment guided by clinical assessment alone?

All‐cause mortality · patients with heart failure

Does treatment guided by serial BNP or NT‐proBNP monitoring improve… showed no clear difference in all‐cause mortality compared with treatment guided by clinical assessment alone? (low certainty).

1 finding from 1 review

clopidogrel plus aspirin vs aspirin

Cardiovascular mortality · people with coronary disease, ischaemic cerebrovascular disease, peripheral arterial disease or at high risk of atherothrombotic disease

clopidogrel plus aspirin showed no clear difference in cardiovascular mortality compared with aspirin alone (moderate certainty).

1 finding from 1 review