Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

559 questions · 576 findings · 177 reviews

No studies found 140 · 24.3%GRADE not reported 45 · 7.8%Very low 184 · 31.9%Low 131 · 22.7%Moderate 60 · 10.4%High 16 · 2.8%

Comparison 1: antibiotic alone or antibiotic with other newborn care interventions vs usual care

Neonatal mortality · neonates with sepsis

Comparison 1: antibiotic alone or antibiotic with other newborn care… showed no clear difference in neonatal mortality ‐ antibiotics alone compared with standard care (moderate certainty).

2 findings from 1 review

Community health educational intervention for family members and mothers and for mothers only (subgroup) vs control

Neonatal mortality ‐ Intervention given to mothers only · developing countries

It is very uncertain whether community health educational intervention for family members and… changes neonatal mortality ‐ Intervention given to mothers only compared with control (very low certainty).

1 finding from 1 review

Community health educational intervention for family members and mothers and for mothers only (subgroup) vs control

Perinatal mortality · developing countries

Community health educational intervention for family members and… may leads to lower perinatal mortality ‐ Intervention given to mothers and family members compared with control (low certainty).

2 findings from 1 review

Community health educational intervention for family members and mothers and for mothers only (subgroup) vs control

Late neonatal mortality ‐ Intervention given to mothers only · developing countries

It is very uncertain whether community health educational intervention for family members and… changes late neonatal mortality ‐ Intervention given to mothers only compared with control (very low certainty).

1 finding from 1 review

Community health educational intervention for family members and mothers and for mothers only (subgroup) vs control

Early neonatal mortality ‐ Intervention given to mothers only · developing countries

It is very uncertain whether community health educational intervention for family members and… changes early neonatal mortality ‐ Intervention given to mothers only compared with control (very low certainty).

1 finding from 1 review

Single‐component medication monitoring and adjustment intervention vs control

All‐cause mortality · people at risk of delirium in institutional long‐term care

Single‐component medication monitoring and adjustment intervention showed no clear difference in mortality compared with control (moderate certainty).

1 finding from 1 review

Community health educational intervention for family members and mothers and for mothers only (subgroup) vs control

Neonatal mortality · developing countries

Community health educational intervention for family members and… may leads to lower neonatal mortality ‐ Intervention given to mothers and family members compared with control (low certainty).

1 finding from 1 review

Community health educational intervention for family members and mothers and for mothers only (subgroup) vs control

Late neonatal mortality ‐ Intervention given to mothers and family members · developing countries

Community health educational intervention for family members and… may leads to lower late neonatal mortality ‐ Intervention given to mothers and family… compared with control (low certainty).

1 finding from 1 review

Community health educational intervention for family members and mothers and for mothers only (subgroup) vs control

Early neonatal mortality ‐ Intervention given to mothers and family members · developing countries

It is very uncertain whether community health educational intervention for family members and… changes early neonatal mortality ‐ Intervention given to mothers and family… compared with control (very low certainty).

1 finding from 1 review

Self‐management interventions vs usual care

All‐cause mortality · patients with chronic obstructive pulmonary disease

Self‐management interventions showed no clear difference in all‐cause mortality compared with usual care (low certainty).

2 findings from 2 reviews · compare the 2 reviews

Self‐management interventions vs usual care

Respiratory‐related mortality · patients with chronic obstructive pulmonary disease

Self‐management interventions showed no clear difference in respiratory‐related mortality compared with usual care (low certainty).

2 findings from 2 reviews · compare the 2 reviews

Adverse event outcomes for dietary combined with physical activity interventions vs standard‐of‐care therapy

Perinatal mortality · pregnant women, excluding women already diagnosed with GDM in this pregnancy and those with pre‐existing diabetes mellitus

Combined diet and exercise interventions showed no clear difference in perinatal mortality compared with standard care (child) (low certainty).

1 finding from 1 review