What do systematic reviews say?

Modified B‐Lynch compression suture technique vs standard B‐Lynch compression suture (one uterine compression suture technique versus another uterine compression suture technique)

The review found no eligible studies for this question.

• Mechanical and surgical interventions for treating primary postpartum haemorrhage 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Angiotensin‐converting enzyme inhibitors vs vitamin C

The review found no eligible studies for this question.

• Interventions for chronic kidney disease in people with sickle cell disease 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

IVIg vs corticosteroids

The review found no eligible studies for this question.

• Systemic interventions for treatment of Stevens‐Johnson syndrome (SJS), toxic epidermal necrolysis (TEN), and SJS/TEN… 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Proton pump inhibitors (PPI) vs placebo or no prophylaxis

Proton pump inhibitors showed no clear difference in all‐cause mortality in ICU compared with placebo or no prophylaxis (low certainty).

• Interventions for preventing upper gastrointestinal bleeding in people admitted to intensive care units 2018 · Cochrane Headline outcomes only
  RR 1.09 [0.6, 1.99]
  3 studies · 258 participants
  Low

Antacids vs placebo or no prophylaxis

Antacids showed no clear difference in all‐cause mortality in ICU compared with placebo or no prophylaxis (low certainty).

• Interventions for preventing upper gastrointestinal bleeding in people admitted to intensive care units 2018 · Cochrane Headline outcomes only
  RR 1.01 [0.53, 1.96]
  2 studies · 300 participants
  Low

Sucralfate vs placebo or no prophylaxis

Sucralfate showed no clear difference in all‐cause mortality in ICU compared with placebo or no prophylaxis (low certainty).

• Interventions for preventing upper gastrointestinal bleeding in people admitted to intensive care units 2018 · Cochrane Headline outcomes only
  RR 0.97 [0.66, 1.43]
  5 studies · 500 participants
  Low

H2 receptor antagonists vs proton pump inhibitors

H2 receptor antagonists showed no clear difference in all‐cause mortality in ICU compared with proton pump inhibitors (low certainty).

• Interventions for preventing upper gastrointestinal bleeding in people admitted to intensive care units 2018 · Cochrane Headline outcomes only
  RR 0.96 [0.78, 1.19]
  12 studies · 1564 participants
  Low

H2 receptor antagonists vs antacids

It is very uncertain whether H2 receptor antagonists changes all‐cause mortality in ICU compared with antacids (very low certainty).

• Interventions for preventing upper gastrointestinal bleeding in people admitted to intensive care units 2018 · Cochrane Headline outcomes only
  RR 1.01 [0.66, 1.55]
  11 studies · 1321 participants
  Very low

H2 receptor antagonists vs sucralfate

H2 receptor antagonists showed no clear difference in all‐cause mortality in ICU compared with sucralfate (low certainty).

• Interventions for preventing upper gastrointestinal bleeding in people admitted to intensive care units 2018 · Cochrane Headline outcomes only
  RR 1.09 [0.95, 1.24]
  21 studies · 3178 participants
  Low

Antacids vs sucralfate

Antacids showed no clear difference in all‐cause mortality in ICU compared with sucralfate (low certainty).

• Interventions for preventing upper gastrointestinal bleeding in people admitted to intensive care units 2018 · Cochrane Headline outcomes only
  RR 1.15 [0.93, 1.4]
  11 studies · 1249 participants
  Low

H2 receptor antagonists vs placebo or no prophylaxis

H2 receptor antagonists showed no clear difference in all‐cause mortality in ICU compared with placebo or no prophylaxis (low certainty).

• Interventions for preventing upper gastrointestinal bleeding in people admitted to intensive care units 2018 · Cochrane Headline outcomes only
  RR 1.12 [0.88, 1.42]
  14 studies · 1428 participants
  Low

Test‐based attendance vs routine isolation after contact with a SARS‐CoV‐2 positive person

The review found no eligible studies for this question.

• Workplace interventions to reduce the risk of SARS‐CoV‐2 infection outside of healthcare settings 2024 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intervention not reported

It is very uncertain whether the intervention changes hospital or 30‐day mortality (very low certainty).

• Effects of interventions targeting the systemic inflammatory response to cardiac surgery on clinical outcomes in adults 2023 · Cochrane Headline outcomes only
  RR 0.78 [0.68, 0.91]
  190 studies · 24817 participants
  Very low

Elective neck dissection (at time of primary tumour resection) vs Therapeutic (delayed) neck dissection

Elective neck dissection (at time of primary tumour resection) probably leads to lower mortality (overall survival) compared with therapeutic (delayed) neck dissection (moderate certainty).

• Interventions for the treatment of oral cavity and oropharyngeal cancers: surgical treatment 2023 · Cochrane All outcomes

  3 years
  HR 0.64 [0.50, 0.83]
  4 studies · 883 participants
  Moderate

Carvedilol vs placebo

• Pharmacological interventions for treating heart failure in patients with Chagas cardiomyopathy 2016 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 69 participants
  GRADE not reported

Rosuvastatin vs placebo

• Pharmacological interventions for treating heart failure in patients with Chagas cardiomyopathy 2016 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 39 participants
  GRADE not reported

An extended ZDV/3TC/LPV/r regimen administered to mothers vs an extended ZDV/3TC/ABC administered to mothers

An extended ZDV/3TC/LPV/r regimen administered to mothers showed no clear difference in infant Mortality at 6 months compared with an extended ZDV/3TC/ABC administered to mothers (low certainty).

• Antiretroviral interventions for preventing breast milk transmission of HIV 2014 · Cochrane Headline outcomes only
  RR 1.05 [0.37, 2.95]
  1 study · 553 participants
  Low

An extended ZDV/3TC/LPV/r regimen administered to mothers vs Short‐Course AZT (intrapartum AZT/3TC/sd‐NVP)

An extended ZDV/3TC/LPV/r regimen administered to mothers showed no clear difference in infant Mortality at 6 months compared with short course ZDV (intrapartum ZDV/3TC/sdNVP) (low certainty).

• Antiretroviral interventions for preventing breast milk transmission of HIV 2014 · Cochrane Headline outcomes only
  HR 0.88 [0.36, 2.11]
  1 study · 624 participants
  Low

Intervention not reported

The review found no eligible studies for this question.

• Education, incentive, and engineering‐based interventions to promote the use of seat belts 2024 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intervention not reported

The review found no eligible studies for this question.

• Education, incentive, and engineering‐based interventions to promote the use of seat belts 2024 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found