Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

74 questions · 74 findings · 26 reviews

No studies found 33 · 44.6%GRADE not reported 10 · 13.5%Very low 16 · 21.6%Low 13 · 17.6%Moderate 2 · 2.7%High 0 · 0%

Summary of findings table ‐ Low‐carbohydrate weight‐reducing diets vs balanced‐carbohydrate weight‐reducing diets

Cardiovascular mortality ‐ not measured · overweight and obese participants without T2DM (weight‐reducing phase followed by weight maintenance phase)

The review found no eligible studies for this question.

1 finding from 1 review

Summary of findings table ‐ Low‐carbohydrate weight‐reducing diets vs balanced‐carbohydrate weight‐reducing diets

Cardiovascular mortality ‐ not measured · overweight and obese participants with T2DM (weight‐reducing phase only)

The review found no eligible studies for this question.

1 finding from 1 review

Summary of findings table ‐ Low‐carbohydrate weight‐reducing diets vs balanced‐carbohydrate weight‐reducing diets

Cardiovascular mortality ‐ not measured · overweight and obese participants with T2DM (weight‐reducing phase followed by weight‐maintenance phase)

The review found no eligible studies for this question.

1 finding from 1 review

Summary of findings table ‐ Low‐carbohydrate weight‐reducing diets vs balanced‐carbohydrate weight‐reducing diets

Cardiovascular mortality ‐ not measured · overweight and obese participants without T2DM (weight‐reducing phase only)

The review found no eligible studies for this question.

1 finding from 1 review

Adverse event outcomes for dietary combined with physical activity interventions vs usual care

All‐cause mortality · people at increased risk for developing type 2 diabetes

It is very uncertain whether diet plus physical activity changes all‐cause mortality compared with standard treatment (very low certainty).

1 finding from 1 review

Adverse event outcomes for dietary combined with physical activity interventions vs standard‐of‐care therapy

Perinatal mortality · pregnant women, excluding women already diagnosed with GDM in this pregnancy and those with pre‐existing diabetes mellitus

Combined diet and exercise interventions showed no clear difference in perinatal mortality compared with standard care (child) (low certainty).

1 finding from 1 review

Adverse event outcomes for dietary combined with physical activity interventions vs usual care

Cardiovascular mortality · people at increased risk for developing type 2 diabetes

It is very uncertain whether diet plus physical activity changes cardiovascular mortality compared with standard treatment (very low certainty).

1 finding from 1 review

Nutritional supplement (500ml) and standard diet vs standard diet

Mortality during time on waiting list (ITT) · adult patients before and after liver transplantation.

It is very uncertain whether nutritional supplement (500ml) and standard diet changes mortality during time on waiting list (ITT) compared with standard diet alone (very low certainty).

1 finding from 1 review

Supportive interventions for enhancing dietary intake vs comparators

All‐cause mortality · malnourished or nutritionally at‐risk adults

Supportive interventions for enhancing dietary intake probably leads to lower all‐cause mortality compared with comparators (moderate certainty).

1 finding from 1 review

Nutritional supplement (500ml) and standard diet vs standard diet

Six months mortality after liver transplantation (ITT) · adult patients before and after liver transplantation.

It is very uncertain whether nutritional supplement (500ml) and standard diet changes six months mortality after liver transplantation (ITT) compared with standard diet alone (very low certainty).

1 finding from 1 review