What do systematic reviews say?

PUL vs sham

It is very uncertain whether PUL changes major adverse events compared with sham (very low certainty).

• Prostatic urethral lift for the treatment of lower urinary tract symptoms in men with benign prostatic hyperplasia 2019 · Cochrane Headline outcomes only
  RR 3.3 [0.41, 26.28]
  1 study · 206 participants
  Very low

PUL vs TURP

It is very uncertain whether PUL changes major adverse events compared with TURP (very low certainty).

• Prostatic urethral lift for the treatment of lower urinary tract symptoms in men with benign prostatic hyperplasia 2019 · Cochrane Headline outcomes only
  RR 0.64 [0.18, 2.19]
  1 study · 79 participants
  Very low
• Prostatic urethral lift for the treatment of lower urinary tract symptoms in men with benign prostatic hyperplasia 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Alpha‐blocker as adjuvant medical expulsive therapy plus usual care vs usual care

• Alpha‐blockers after shock wave lithotripsy for renal or ureteral stones in adults 2020 · Cochrane Headline outcomes only
  no estimate extracted
  7 studies · 747 participants
  Low

Alpha‐blockers vs usual care

Alpha‐blockers showed no clear difference in major adverse events compared with standard therapy (low certainty).

• Alpha‐blockers as medical expulsive therapy for ureteral stones 2018 · Cochrane Headline outcomes only
  RR 1.25 [0.8, 1.96]
  18 studies · 3124 participants
  Low

Alpha‐blockers vs placebo

Alpha‐blockers probably leads to higher major adverse events compared with placebo (moderate certainty).

• Alpha‐blockers as medical expulsive therapy for ureteral stones 2018 · Cochrane Headline outcomes only
  RR 2.09 [1.13, 3.86]
  10 studies · 1650 participants
  Moderate