Alpha‐blockers vs placebo: Major adverse events
Alpha‐blockers probably leads to higher major adverse events compared with placebo (moderate certainty).
What each review found
Include earlier review versions| Finding | Effect | Studies | GRADE certainty |
|---|---|---|---|
Alpha‐blockers vs placebo Major adverse events · adult patients presenting with symptoms of ureteral stone disease Alpha‐blockers probably leads to higher major adverse events compared with placebo (moderate certainty). Alpha‐blockers as medical expulsive therapy for ureteral stones (2018) · Cochrane Headline outcomes only | RR 2.09 [1.13, 3.86] | 10 studies · 1650 participants | Moderate |
Findings are shown side by side, never pooled across reviews.
The reviews
| Review | Searched up to | Included studies | AMSTAR 2 |
|---|---|---|---|
| Alpha‐blockers as medical expulsive therapy for ureteral stones 2018 · Cochrane Headline outcomes only | Not reported | list not extracted yet | Not assessed |
Studies behind the findings
None of these reviews ties its included studies to this outcome in the data here. Cochrane reviews and reviews with headline outcomes only do not list their studies yet.
How reviews are matched to this question
Reviews word the same question differently. Four decision models (TypeSafe's Jev, Liquid AI's d1-ultra, SubQ Snap and Baseten's Elephant) judged each wording of the population, intervention, comparator and outcome against the others; two wordings count as the same when at least three of them agree and none clearly disagrees, and findings count as this question only when all four elements match. Timing, setting and subgroup never split a question: they are shown on each finding.