Findings

What do systematic reviews say?

3 questions · 3 findings · 2 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 66.7%Moderate 1 · 33.3%High 0 · 0%

Major adverse events · adult patients presenting with symptoms of ureteral stone disease

Alpha‐blockers showed no clear difference in major adverse events compared with standard therapy (low certainty).

1 finding from 1 review

Alpha‐blockers as medical expulsive therapy for ureteral stones 2018 · Cochrane Headline outcomes only
RR 1.25 [0.8, 1.96]
18 studies · 3124 participants
Low

Major adverse events · adult patients presenting with symptoms of ureteral stone disease

Alpha‐blockers probably leads to higher major adverse events compared with placebo (moderate certainty).

1 finding from 1 review

Alpha‐blockers as medical expulsive therapy for ureteral stones 2018 · Cochrane Headline outcomes only
RR 2.09 [1.13, 3.86]
10 studies · 1650 participants
Moderate

Major adverse events · adults with renal and ureteral stones undergoing shock wave lithotripsy

1 finding from 1 review

Alpha‐blockers after shock wave lithotripsy for renal or ureteral stones in adults 2020 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 747 participants
Low