Findings

What do systematic reviews say?

2 questions · 2 findings · 2 reviews · Emergency and Critical Care

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 50%Moderate 1 · 50%High 0 · 0%

Corticosteroids vs placebo or usual care

Long‐term mortalityc · children and adults with sepsis

Corticosteroids showed no clear difference in long‐term mortalityc compared with placebo or usual care (low certainty).

1 finding from 1 review

Corticosteroids for treating sepsis in children and adults 2019 · Cochrane Headline outcomes only
RR 0.97 [0.91, 1.03]
7 studies · 6236 participants
Low

Glutamine‐supplemented nutrition vs non‐supplemented nutrition

Long‐term mortality (closest to six month) · critically ill patients or receiving major surgery

Glutamine‐supplemented nutrition showed no clear difference in long‐term mortality (closest to six month) compared with non‐supplemented nutrition (moderate certainty).

1 finding from 1 review

Glutamine supplementation for critically ill adults 2014 · Cochrane Headline outcomes only
RR 1 [0.89, 1.12]
11 studies · 2277 participants
Moderate