Findings

What do systematic reviews say?

4 questions · 4 findings · 3 reviews · Gynaecology and Fertility

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 25%Low 3 · 75%Moderate 0 · 0%High 0 · 0%

Single vs multiple embryo transfer

Live birth · transfer following in vitro fertilisation or intracytoplasmic sperm injection

Single may leads to lower live birth compared with multiple embryo transfer (low certainty).

1 finding from 1 review

Number of embryos for transfer following in vitro fertilisation or intra‐cytoplasmic sperm injection 2020 · Cochrane Headline outcomes only
RR 0.67 [0.59, 0.75]
12 studies · 1904 participants
Low

Repeated single embryo transfer (mixed policies) vs multiple embryo transfer

Cumulative live birth · transfer following in vitro fertilisation or intracytoplasmic sperm injection

Repeated single embryo transfer (mixed policies) showed no clear difference in cumulative live birth compared with multiple embryo transfer (low certainty).

1 finding from 1 review

Number of embryos for transfer following in vitro fertilisation or intra‐cytoplasmic sperm injection 2020 · Cochrane Headline outcomes only
RR 0.95 [0.82, 1.1]
4 studies · 985 participants
Low

Day 5 vs day 3 embryo biopsy

Live birth · people having preimplantation genetic testing for monogenic/single gene defects

It is very uncertain whether day 5 changes live birth compared with day 3 embryo biopsy (very low certainty).

1 finding from 1 review

Day 5 versus day 3 embryo biopsy for preimplantation genetic testing for monogenic/single gene defects 2022 · Cochrane Headline outcomes only
OR 1.5 [0.26, 8.82]
1 study · 20 participants
Very low

Double intrauterine insemination (IUI) vs single IUI

Live birth rate · stimulated cycles for subfertile couples

Double intrauterine insemination (IUI) showed no clear difference in live birth ratea compared with single IUI (low certainty).

1 finding from 1 review

Double versus single intrauterine insemination (IUI) in stimulated cycles for subfertile couples 2021 · Cochrane Headline outcomes only
OR 1.15 [0.71, 1.88]
3 studies · 468 participants
Low