Findings

What do systematic reviews say?

3 questions · 3 findings · 2 reviews · Gynaecology and Fertility

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No studies found 1 · 33.3%GRADE not reported 0 · 0%Very low 1 · 33.3%Low 1 · 33.3%Moderate 0 · 0%High 0 · 0%

Embryo culture supernatant injection vs no intervention

Live birth or ongoing pregnancy · Subfertile women undergoing assisted reproduction

It is very uncertain whether embryo culture supernatant injection changes live birth/ongoing pregnancy compared with no intervention (very low certainty).

1 finding from 1 review

Endometrial injection of embryo culture supernatant for subfertile women in assisted reproduction 2020 · Cochrane Headline outcomes only
OR 1.11 [0.73, 1.7]
3 studies · 340 participants
Very low

Embryo culture supernatant vs culture medium injection

Live birth or ongoing pregnancy · Subfertile women undergoing assisted reproduction

The review found no eligible studies for this question.

1 finding from 1 review

Endometrial injection of embryo culture supernatant for subfertile women in assisted reproduction 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

GnRHa depot vs GnRHa daily injection

Ongoing pregnancy / live birth rate per woman · women undergoing pituitary suppression in assisted reproduction

GnRHa depot showed no clear difference in live birth/ongoing pregnancy rate per woman Delivery of one or more… compared with gnRHa daily injection (low certainty).

1 finding from 1 review

Depot versus daily administration of gonadotrophin‐releasing hormone agonist protocols for pituitary down regulation… 2013 · Cochrane Headline outcomes only
OR 0.95 [0.7, 1.31]
7 studies · 873 participants
Low