Findings

What do systematic reviews say?

6 questions · 6 findings · 3 reviews · Schizophrenia

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No studies found 0 · 0%GRADE not reported 2 · 33.3%Very low 4 · 66.7%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Switch to a specific antipsychotic vs switch to a different specific antipsychotic

Leaving the study early · patients with antipsychotic‐induced tardive dyskinesia

1 finding from 1 review

Antipsychotic reduction and/or cessation and antipsychotics as specific treatments for tardive dyskinesia 2018 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 466 participants
Very low

SWITCHING ANTIPSYCHOTIC: TO QUETIAPINE vs MAINTENANCE RISPERIDONE

Leaving the study early · patients with sexual dysfunction due to antipsychotic drug therapy

It is very uncertain whether SWITCHING ANTIPSYCHOTIC: TO QUETIAPINE changes leaving the study early compared with MAINTENANCE RISPERIDONE (very low certainty).

1 finding from 1 review

Management of sexual dysfunction due to antipsychotic drug therapy 2012 · Cochrane Headline outcomes only
RR 2.2 [0.45, 10.74]
1 study · 42 participants
Very low

SWITCHING ANTIPSYCHOTIC: TO OLANZAPINE vs MAINTENANCE RISPERIDONE/FGA

Leaving the study early · patients with sexual dysfunction due to antipsychotic drug therapy

It is very uncertain whether SWITCHING ANTIPSYCHOTIC: TO OLANZAPINE changes leaving the study early compared with MAINTENANCE RISPERIDONE/FGA (very low certainty).

1 finding from 1 review

Management of sexual dysfunction due to antipsychotic drug therapy 2012 · Cochrane Headline outcomes only
RR 2.25 [0.79, 6.43]
1 study · 54 participants
Very low

Switch to another antipsychotic vs antipsychotic cessation

Leaving the study early · psychiatric patients (schizophrenia) with antipsychotic‐induced tardive dyskinesia

It is very uncertain whether switch to another antipsychotic changes acceptability of the treatment: leaving the study early compared with antipsychotic cessation (very low certainty).

1 finding from 1 review

Antipsychotic reduction and/or cessation and antipsychotics as specific treatments for tardive dyskinesia 2018 · Cochrane Headline outcomes only
RR 0.6 [0.16, 2.25]
1 study · 50 participants
Very low

Antipsychotic dose increase vs switching the antipsychotic drug

Acceptability of treatment ‐ leaving the study early · non response in schizophrenia

1 finding from 1 review

Increasing antipsychotic dose versus switching antipsychotic for non response in schizophrenia 2018 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Antipsychotic dose increase vs switching the antipsychotic drug

Leaving the study early ‐ due to adverse effects (short term) · non response in schizophrenia

1 finding from 1 review

Increasing antipsychotic dose versus switching antipsychotic for non response in schizophrenia 2018 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported