Findings

What do systematic reviews say?

6 questions · 6 findings · 1 reviews · Schizophrenia

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 33.3%Low 3 · 50%Moderate 1 · 16.7%High 0 · 0%

INTEGRATED MODELS OF CARE vs usual care

Lost to treatment · people with both severe mental illness and substance misuse

Integrated models of care showed no clear difference in leaving the study early: Lost to treatment compared with standard care (low certainty).

1 finding from 1 review

Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes only
RR 1.09 [0.82, 1.45]
3 studies · 603 participants
Low

CBT vs usual care

Lost to treatment · people with both severe mental illness and substance misuse

Cognitive behavioural therapy showed no clear difference in leaving the study early: Lost to treatment compared with standard care (low certainty).

1 finding from 1 review

Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes only
RR 1.12 [0.44, 2.86]
2 studies · 152 participants
Low

CONTINGENCY MANAGEMENT vs usual care

Lost to treatment · people with both severe mental illness and substance misuse

Contingency management probably leads to higher leaving the study early: Lost to treatment compared with standard care (moderate certainty).

1 finding from 1 review

Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes only
RR 1.55 [1.13, 2.11]
2 studies · 255 participants
Moderate

SKILLS TRAINING vs usual care

Lost to treatment · people with both severe mental illness and substance misuse

It is very uncertain whether skills training changes leaving the study early: Lost to treatment compared with standard care (very low certainty).

1 finding from 1 review

Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes only
RR 1.42 [0.2, 10.1]
3 studies · 122 participants
Very low

COGNITIVE BEHAVIOUR THERAPY + MOTIVATIONAL INTERVIEWING vs usual care

Lost to treatment · people with both severe mental illness and substance misuse

Cognitive behavioural therapy + motivational interviewing showed no clear difference in leaving the study early: Lost to treatment compared with standard care (low certainty).

1 finding from 1 review

Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes only
RR 0.99 [0.62, 1.59]
1 study · 327 participants
Low

Non‐integrated models of care ‐ Assertive community treatment only/Intensive case management/Specialised case management services vs usual care

Lost to treatment · people with both severe mental illness and substance misuse

It is very uncertain whether non‐integrated models of care ‐ Assertive community treatment… changes leaving the study early: Lost to treatment compared with standard care (very low certainty).

1 finding from 1 review

Psychosocial interventions for people with both severe mental illness and substance misuse 2019 · Cochrane Headline outcomes only
RR 1.21 [0.73, 1.99]
3 studies · 134 participants
Very low