Non-syndromic cleft lip and palate (CLP) status and its oral microbiota (exposure/grouping) vs Children and adolescents aged 0-18 years without CLP (controls)
Lactobacillus spp. salivary/plaque counts (cariogenic microbiota) · Children and adolescents aged 0-18 years with non-syndromic cleft lip and palate (CLP)
A meta-analysis found no significant difference in mean Lactobacillus spp. levels between children with and without CLP, with high heterogeneity; the evidence is ungraded.
1 finding from 1 review
- Characterization of the oral microbiota and the relationship of the oral microbiota with the dental and periodontal… 2024 All outcomesMultiple countries; pediatric cleft/craniofacial care; saliva, dental plaque, subgingival plaque and nasal/oropharyngeal samplesFor the outcome of the presence of Lactobacillus spp., there were no significant differences between patients with CLP and healthy patients, and the diversity of the studies led to high heterogeneity; however, the p…Studies not reportedGRADE not reported