Findings

What do systematic reviews say?

3 questions · 3 findings · 2 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 2 · 66.7%High 1 · 33.3%

Inactivated influenza vaccine vs placebo or no intervention

Influenza assessed by laboratory confirmation · healthy adults

Inactivated parenteral influenza vaccine probably leads to lower influenza assessed by laboratory confirmation Timing of assessment:… compared with placebo or 'do nothing' (moderate certainty).

1 finding from 1 review

Vaccines for preventing influenza in healthy adults 2018 · Cochrane Headline outcomes only
RR 0.41 [0.36, 0.47]
25 studies · 71221 participants
Moderate

Inactivated influenza vaccine vs placebo or no intervention

Influenza assessed by laboratory confirmation · healthy, community‐dwelling children older than 2 years of age

Inactivated influenza vaccine leads to lower influenza assessed by laboratory confirmation compared with placebo or do nothing (high certainty).

1 finding from 1 review

Vaccines for preventing influenza in healthy children 2018 · Cochrane Headline outcomes only
RR 0.36 [0.28, 0.48]
5 studies · 1628 participants
High

Live attenuated influenza vaccine vs placebo or no intervention

Influenza assessed by laboratory confirmation · healthy, community‐dwelling children younger than 16 years of age

Live attenuated influenza vaccine probably leads to lower influenza assessed by laboratory confirmation compared with placebo or do nothing (moderate certainty).

1 finding from 1 review

Vaccines for preventing influenza in healthy children 2018 · Cochrane Headline outcomes only
RR 0.22 [0.11, 0.41]
7 studies · 7718 participants
Moderate