Findings

What do systematic reviews say?

3 questions · 3 findings · 2 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 33.3%Moderate 2 · 66.7%High 0 · 0%

Inactivated influenza vaccine vs placebo or no intervention

Influenza‐like illness · healthy adults

Inactivated parenteral influenza vaccine probably leads to lower influenza‐like illness assessed by subjective report Timing of… compared with placebo or 'do nothing' (moderate certainty).

1 finding from 1 review

Vaccines for preventing influenza in healthy adults 2018 · Cochrane Headline outcomes only
RR 0.84 [0.75, 0.95]
16 studies · 25795 participants
Moderate

Inactivated influenza vaccine vs placebo or no intervention

Influenza‐like illness · healthy, community‐dwelling children older than 2 years of age

Inactivated influenza vaccine probably leads to lower influenza‐like illness assessed by subjective report compared with placebo or do nothing (moderate certainty).

1 finding from 1 review

Vaccines for preventing influenza in healthy children 2018 · Cochrane Headline outcomes only
RR 0.72 [0.65, 0.79]
4 studies · 19044 participants
Moderate

Live attenuated influenza vaccine vs placebo or no intervention

Influenza‐like illness · healthy, community‐dwelling children younger than 16 years of age

Live attenuated influenza vaccine may leads to lower influenza‐like illness assessed by subjective report compared with placebo or do nothing (low certainty).

1 finding from 1 review

Vaccines for preventing influenza in healthy children 2018 · Cochrane Headline outcomes only
RR 0.69 [0.6, 0.8]
7 studies · 124606 participants
Low