Evidence Gaps

What do systematic reviews say?

1 questions · 3 findings · 1 reviews · Drugs and Alcohol

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 66.7%Moderate 1 · 33.3%High 0 · 0%

Full opioid agonists vs different full opioid agonists or partial opioid agonists (methadone versus buprenorphine)

Illicit opioid use · pharmaceutical opioid dependent people

Full opioid agonists showed no clear difference in illicit opioid use compared with different full opioid agonists or partial opioid agonists (methadone… (moderate certainty).

3 findings from 1 review

Opioid agonist treatment for people who are dependent on pharmaceutical opioids 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 129 participants
Moderate
Opioid agonist treatment for people who are dependent on pharmaceutical opioids 2022 · Cochrane Headline outcomes only
RR 0.81 [0.57, 1.17]
3 studies · 206 participants
Low
Opioid agonist treatment for people who are dependent on pharmaceutical opioids 2022 · Cochrane Headline outcomes only
RR 0.49 [0.28, 0.86]
3 studies · 165 participants
Low