Findings

What do systematic reviews say?

3 questions · 3 findings · 3 reviews · Pregnancy and Childbirth

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No studies found 0 · 0%GRADE not reported 1 · 33.3%Very low 1 · 33.3%Low 0 · 0%Moderate 1 · 33.3%High 0 · 0%

Insulin vs anti‐diabetic agent

Hypertensive disorders of pregnancy: pre‐eclampsia · women with gestational diabetes mellitus

Insulin showed no clear difference in hypertensive disorders of pregnancy (pre‐eclampsia) compared with anti‐diabetic agent (moderate certainty).

1 finding from 1 review

Insulin for the treatment of women with gestational diabetes 2017 · Cochrane Headline outcomes only
RR 1.14 [0.86, 1.52]
10 studies · 2060 participants
Moderate

Metformin vs insulin

Hypertensive disorders of pregnancy: pre‐eclampsia · women with type 2 diabetes

It is very uncertain whether maternal outcomes: oral anti‐diabetic agent (metformin) changes hypertensive disorders of pregnancy: pre‐eclampsia compared with insulin (very low certainty).

1 finding from 1 review

Oral anti‐diabetic agents for women with established diabetes/impaired glucose tolerance or previous gestational… 2017 · Cochrane Headline outcomes only
RR 0.63 [0.33, 1.2]
2 studies · 227 participants
Very low

CSII vs MDI: maternal outcomes

Hypertensive disorders of pregnancy · pregnant women with diabetes

1 finding from 1 review

Continuous subcutaneous insulin infusion versus multiple daily injections of insulin for pregnant women with diabetes 2016 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported