Findings

What do systematic reviews say?

69 questions · 70 findings · 40 reviews

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No studies found 24 · 34.3%GRADE not reported 1 · 1.4%Very low 17 · 24.3%Low 10 · 14.3%Moderate 9 · 12.9%High 9 · 12.9%

Mepolizumab 300 mg vs placebo

QoL · patients with chronic obstructive pulmonary disease

1 finding from 1 review

Anti‐IL‐5 therapies for chronic obstructive pulmonary disease 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 451 participants
Moderate

Mepolizumab 100 mg vs placebo

QoL · patients with chronic obstructive pulmonary disease

1 finding from 1 review

Anti‐IL‐5 therapies for chronic obstructive pulmonary disease 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 911 participants
Moderate

Mucolytic vs placebo

SGRQ Total SGRQ (Total) Score. Scale from: 0 to 100. Lower score indicates better quality of life. · chronic bronchitis or COPD

1 finding from 1 review

Mucolytic agents versus placebo for chronic bronchitis or chronic obstructive pulmonary disease 2019 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 2721 participants
Moderate

Cognitive‐behavioural intervention vs controls

Health‐related quality of life end of treatment (0‐80 scale) Higher scores indicate lower health‐related quality of life · patients with fibromyalgia

1 finding from 1 review

Cognitive behavioural therapies for fibromyalgia 2013 · Cochrane Headline outcomes only
no estimate extracted
13 studies · 1238 participants
Low

Serotonin and noradrenaline reuptake inhibitors (SNRI) vs placebo

Self‐reported health‐related quality of life (0‐100 scale) Higher scores indicate higher burden of disease (lower quality of life) · patients with fibromyalgia

Serotonin noradrenaline reuptake inhibitors showed no clear difference in self‐reported health‐related quality of life (0‐100 scale) Higher… compared with placebo (low certainty).

1 finding from 1 review

Serotonin and noradrenaline reuptake inhibitors (SNRIs) for fibromyalgia 2018 · Cochrane Headline outcomes only
no estimate extracted
14 studies · 6861 participants
Low

Information or education intervention vs no education

Health‐related quality of life (HRQoL) · adult ICU patients and their carers

1 finding from 1 review

Information or education interventions for adult intensive care unit (ICU) patients and their carers 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 143 participants
Very low

Pursed lip breathing vs no breathing exercises

Health‐related quality of life Dyspnoea domain of Hiratsuka scale Scores range from 0 to 100, with lower scores indicating less shortness of breath · patients with chronic obstructive pulmonary disease

1 finding from 1 review

Breathing exercises for chronic obstructive pulmonary disease 2012 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 60 participants
Low

Intervention not reported

Health‐related quality of life (disease‐specific) Scale from 0 to 100; lower score indicates better HRQoL. SGRQ total score consists of weighted scores from 3 domains · individuals with stable bronchiectasis

1 finding from 1 review

Airway clearance techniques for bronchiectasis 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 20 participants
Low

Etanercept vs placebo

CDLQI Scores range from 0 to 30. Lower scores indicate better health‐related quality of life. Calculations are based on the change from baseline to week 12 in both groups · people with paediatric psoriasis

1 finding from 1 review

Anti‐TNF agents for paediatric psoriasis 2015 · Cochrane Headline outcomes only
no estimate extracted
1 study · 211 participants
Moderate

tDCS vs sham tDCS

Health‐related quality of life (mental) · Patients with idiopathic Parkinson's disease

1 finding from 1 review

Transcranial direct current stimulation (tDCS) for idiopathic Parkinson's disease 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 25 participants
Very low

tDCS vs sham tDCS

Health‐related quality of life (physical) · Patients with idiopathic Parkinson's disease

1 finding from 1 review

Transcranial direct current stimulation (tDCS) for idiopathic Parkinson's disease 2016 · Cochrane Headline outcomes only
no estimate extracted
1 study · 25 participants
Very low

Intervention not reported

Health‐related quality of life (respiratory specific) St George's Respiratory Questionnaire (SGRQ; total score) Scale from 0‐100 Lower value post intervention is favourable, indicating improvement in health‐related quality of life · people with stable COPD

1 finding from 1 review

Singing for adults with chronic obstructive pulmonary disease 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 58 participants
Low

Less intensive vs more intensive follow‐up after primary cancer treatment

Health‐related quality of life · adult cancer survivors from the following cancer sites: breast, colorectal, head‐and‐neck, Hodgkin lymphoma, melanoma, non‐small cell lung…

1 finding from 1 review

Follow‐up strategies following completion of primary cancer treatment in adult cancer survivors 2019 · Cochrane Headline outcomes only
no estimate extracted
2742 participants
Very low

Non‐specialist‐led vs specialist‐led follow‐up after primary cancer treatment

Health‐related quality of life, (at 12 months' · adult cancer survivors from the following cancer sites: breast, colon, colorectal, endometrial, ovarian, cervical, melanoma and oesophageal

Non‐specialist‐led showed no clear difference in health‐related quality of life, (at 12 months' compared with specialist‐led follow‐up after primary cancer treatment (low certainty).

1 finding from 1 review

Follow‐up strategies following completion of primary cancer treatment in adult cancer survivors 2019 · Cochrane Headline outcomes only
MD 1.06
605 participants
Low