Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

34 questions · 34 findings · 15 reviews

No studies found 13 · 38.2%GRADE not reported 0 · 0%Very low 1 · 2.9%Low 13 · 38.2%Moderate 5 · 14.7%High 2 · 5.9%

Intervention not reported

Global assessment of treatment success Satisfactory pace of recovery · people following primary uncemented THA

It is very uncertain whether the intervention changes global assessment of treatment success Satisfactory pace of recovery (very low certainty).

1 finding from 1 review

Surgery vs non‐surgical treatment

Global assessment of treatment success · people with full‐thickness rotator cuff tears

Surgery showed no clear difference in participant‐rated global assessment of treatment success at 12 months compared with non‐operative treatment (low certainty).

1 finding from 1 review

Low‐dose colchicine vs NSAIDs

Global assessment of treatment success · acute gout

Low‐dose colchicine showed no clear difference in participant global assessment of treatment success: Completely… compared with NSAIDs (low certainty).

1 finding from 1 review

Manual therapy and exercise vs glucocorticoid injection

Global assessment of treatment success · patients with adhesive capsulitis (frozen shoulder)

Combination of manual therapy and exercise probably leads to lower global assessment of treatment success Complete recovery or much… compared with glucocorticoid injection (moderate certainty).

1 finding from 1 review

Combination of manual therapy and exercise following joint distension vs sham ultrasound following joint distension

Global assessment of treatment success · patients with adhesive capsulitis (frozen shoulder)

Combination of manual therapy and exercise following joint distension leads to higher global assessment of treatment success "Success, much improved,… compared with sham ultrasound following joint distension (high certainty).

1 finding from 1 review

MAL‐PDT vs red light only

Investigator's global assessment (IGA) of improvement Treatment 'success' as defined by IGA score decrease5 · Moderate and severe acne vulgaris

MAL‐PDT probably leads to higher investigator's global assessment (IGA) of improvement Treatment… compared with red light only (moderate certainty).

1 finding from 1 review
  • Light therapies for acne 2016 · Cochrane Headline outcomes only
    RR 1.74 [1.11, 2.74]
    3 studies · 360 participants
    Moderate

ALA‐PDT vs blue light only

Investigator's global assessment (IGA) of improvement Treatment 'success' as defined by IGA score decrease5 · Moderate and severe acne vulgaris

ALA‐PDT showed no clear difference in investigator's global assessment (IGA) of improvement Treatment… compared with blue light only (low certainty).

1 finding from 1 review

High‐dose vs low‐dose colchicine

Participant global assessment of treatment success: proportion with 50% or greater decrease in pain score from baseline ‐ 32 to 36 hours · acute gout

High‐dose showed no clear difference in participant global assessment of treatment success: proportion with… compared with low‐dose colchicine (low certainty).

1 finding from 1 review

Low‐dose colchicine vs placebo

Participant global assessment of treatment success: proportion with 50% or greater decrease in pain score from baseline ‐ 32 to 36 hours · acute gout

Low‐dose colchicine may leads to higher participant global assessment of treatment success: proportion with… compared with placebo (low certainty).

1 finding from 1 review

High‐dose colchicine vs placebo

Participant global assessment of treatment success: proportion with 50% or greater decrease in pain score from baseline ‐ 32 to 36 hours · acute gout

High‐dose colchicine may leads to higher participant global assessment of treatment success: proportion with… compared with placebo (low certainty).

1 finding from 1 review

Combination of manual therapy, exercise, electrotherapy and oral NSAID vs oral NSAID

Global assessment of treatment success · patients with adhesive capsulitis (frozen shoulder)

Combination of manual therapy, exercise, electrotherapy and oral NSAID may leads to higher global assessment of treatment success "Disappearance of shoulder… compared with oral NSAID (low certainty).

1 finding from 1 review