Findings

What do systematic reviews say?

19 questions · 26 findings · 6 reviews · Headline outcomes only

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No studies found 1 · 3.8%GRADE not reported 0 · 0%Very low 4 · 15.4%Low 12 · 46.2%Moderate 9 · 34.6%High 0 · 0%

Aerobic exercise vs usual care

Activity Gross motor function · children and adolescents with cerebral palsy

1 finding from 1 review

Exercise interventions for cerebral palsy 2017 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 65 participants
Low

Resistance training vs usual care

Activity Gross motor function · children and adolescents with cerebral palsy

2 findings from 1 review

Exercise interventions for cerebral palsy 2017 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 164 participants
Low
Exercise interventions for cerebral palsy 2017 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 85 participants
Low

Mixed training vs usual care

Activity Gross motor function · children and adolescents with cerebral palsy

1 finding from 1 review

Exercise interventions for cerebral palsy 2017 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 163 participants
Low

Resistance training vs aerobic exercise training

Activity Gross motor function · children with cerebral palsy

1 finding from 1 review

Exercise interventions for cerebral palsy 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 56 participants
Low

Intervention not reported

Effect on physical functioning · Children with cerebral palsy

The review found no eligible studies for this question.

1 finding from 1 review

Sleep positioning systems for children with cerebral palsy 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Mechanically assisted walking training without body weight support vs the same dose of overground walking training

Activity Gross motor function · children with cerebral palsy classified within GMFCS Levels I to III and between 3 and 12 years of age

1 finding from 1 review

Mechanically assisted walking training for walking, participation, and quality of life in children with cerebral palsy 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 35 participants
Moderate

Mechanically assisted walking training with body weight support vs the same dose of overground walking training

Activity Gross motor function · children with cerebral palsy classified within GMFCS Levels I to IV and between 4 and 18 years of age

1 finding from 1 review

Mechanically assisted walking training for walking, participation, and quality of life in children with cerebral palsy 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 52 participants
Low

Mechanically assisted walking training with body weight support vs no walking training

Activity Gross motor function · children with cerebral palsy classified within GMFCS Levels I to V and between 3 and 18 years of age

1 finding from 1 review

Mechanically assisted walking training for walking, participation, and quality of life in children with cerebral palsy 2020 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 58 participants
Low

Mechanically assisted walking training without body weight support vs no walking training

Activity Gross motor function · children with cerebral palsy classified within GMFCS Levels I to III between 5 and 19 years of age

1 finding from 1 review

Mechanically assisted walking training for walking, participation, and quality of life in children with cerebral palsy 2020 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 60 participants
Low

Summary of findings: Trihexyphenidyl vs placebo

Participation in activities of daily living:individual goal setting Measured by: GAS (up to 5 functional goals scored on a 5‐point scale (−2 = much less than expected to +2 = much more than expected); higher score = better than expected outcome) · children with dystonic cerebral palsy

1 finding from 1 review

Trihexyphenidyl for dystonia in cerebral palsy 2018 · Cochrane Headline outcomes only
no estimate extracted
16 participants
Low

Mechanically assisted walking training with body weight support vs no walking training

Mobility · children with cerebral palsy classified within GMFCS Levels I to V and between 3 and 18 years of age

1 finding from 1 review

Mechanically assisted walking training for walking, participation, and quality of life in children with cerebral palsy 2020 · Cochrane Headline outcomes only
no estimate extracted
7 studies · 161 participants
Moderate

Mechanically assisted walking training with body weight support vs the same dose of overground walking training

Mobility · children with cerebral palsy classified within GMFCS Levels I to IV and between 4 and 18 years of age

1 finding from 1 review

Mechanically assisted walking training for walking, participation, and quality of life in children with cerebral palsy 2020 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 78 participants
Low

BoNT‐A vs usual care or physiotherapy

Function · children with CP

3 findings from 1 review

Botulinum toxin type A in the treatment of lower limb spasticity in children with cerebral palsy 2019 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 191 participants
Very low
Botulinum toxin type A in the treatment of lower limb spasticity in children with cerebral palsy 2019 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 199 participants
Very low
Botulinum toxin type A in the treatment of lower limb spasticity in children with cerebral palsy 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 123 participants
Very low

BoNT‐A vs sham

Function · children with CP

3 findings from 1 review

Botulinum toxin type A in the treatment of lower limb spasticity in children with cerebral palsy 2019 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 305 participants
Moderate
Botulinum toxin type A in the treatment of lower limb spasticity in children with cerebral palsy 2019 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 327 participants
Moderate
Botulinum toxin type A in the treatment of lower limb spasticity in children with cerebral palsy 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 91 participants
Moderate

BoNT‐A vs serial casting

Function · children with CP

3 findings from 1 review

Botulinum toxin type A in the treatment of lower limb spasticity in children with cerebral palsy 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 18 participants
Moderate
Botulinum toxin type A in the treatment of lower limb spasticity in children with cerebral palsy 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 41 participants
Moderate
Botulinum toxin type A in the treatment of lower limb spasticity in children with cerebral palsy 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 18 participants
Moderate

BoNT‐A vs orthoses

Function · children with CP

1 finding from 1 review

Botulinum toxin type A in the treatment of lower limb spasticity in children with cerebral palsy 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 43 participants
Very low

Intervention not reported

Gross motor function (GMFM) (%) · children under six years with cerebral palsy or Down syndrome or at risk of neuromotor delay

1 finding from 1 review

Treadmill interventions in children under six years of age at risk of neuromotor delay 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 36 participants
Moderate

Intervention not reported

Gross motor function related to standing (GMFM) ‐ Dimension D (%) · children under six years with cerebral palsy or Down syndrome or at risk of neuromotor delay

1 finding from 1 review

Treadmill interventions in children under six years of age at risk of neuromotor delay 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 32 participants
Low

Intervention not reported

Gross motor function related to walking, running and jumping (GMFM) ‐ Dimension E (%) · children under six years with cerebral palsy or Down syndrome or at risk of neuromotor delay

1 finding from 1 review

Treadmill interventions in children under six years of age at risk of neuromotor delay 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 32 participants
Low