Findings

What do systematic reviews say?

3 questions · 4 findings · 2 reviews · Gut

No studies found 1 · 25%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 2 · 50%High 1 · 25%

Failure to induce clinical remission at end of study · Patients with active Crohn's disease

Antibiotic leads to lower failure to enter clinical remission compared with placebo (high certainty).

1 finding from 1 review

Antibiotics for induction and maintenance of remission in Crohn's disease 2019 · Cochrane Headline outcomes only
RR 0.86 [0.76, 0.98]
7 studies · 773 participants
High

Failure to induce clinical remission at end of study · Patients with active Crohn's disease

The review found no eligible studies for this question.

1 finding from 1 review

Antibiotics for induction and maintenance of remission in Crohn's disease 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Failure to induce clinical remission at end of study · patients with induction of remission in ulcerative colitis

Etrolizumab probably leads to lower failure to enter clinical remission at week 10 compared with placebo (moderate certainty).

2 findings from 1 review

Etrolizumab for induction of remission in ulcerative colitis 2015 · Cochrane Headline outcomes only
RR 0.86 [0.77, 0.95]
1 study · 119 participants
Moderate
Etrolizumab for induction of remission in ulcerative colitis 2015 · Cochrane Headline outcomes only
RR 0.81 [0.68, 0.96]
1 study · 59 participants
Moderate