Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3 questions · 3 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 3 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Orthodontic adhesive/composite containing nano-calcium fluoride (n-CaF2), alone or with DMAHDM vs Conventional/control orthodontic adhesive (e.g., Transbond XT) or negative control

Enamel remineralization extent · Human enamel specimens around orthodontic brackets (in vitro)

In vitro, a nano-CaF2-containing orthodontic cement showed significant enamel remineralization versus control in a single study (ungraded).

1 finding from 1 review

Orthodontic adhesives containing nano-amorphous calcium phosphate (n-ACP) particles/nanoparticles vs Conventional/control orthodontic adhesive (e.g., Transbond XT) or negative control

Enamel remineralization extent · Human enamel specimens around orthodontic brackets (in vitro)

In vitro, n-ACP-containing orthodontic adhesives showed significant enamel remineralization versus control in both studies, but evidence is weak (only 2 studies; ungraded).

1 finding from 1 review

Experimental orthodontic adhesive containing amorphous fluorinated calcium phosphate nanoparticles (n-AFCP) vs Conventional/control orthodontic adhesive (e.g., Transbond XT) or negative control

Enamel remineralization extent and color change · Human enamel specimens around orthodontic brackets (in vitro)

In vitro, an n-AFCP-containing orthodontic primer showed significant enamel remineralization and less color change versus control in a single study (ungraded).

1 finding from 1 review