Findings

What do systematic reviews say?

6 questions · 8 findings · 2 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 12.5%Low 7 · 87.5%Moderate 0 · 0%High 0 · 0%

Ectopic pregnancy rate per couple · participants with unexplained subfertility

It is very uncertain whether IUI in a stimulated cycle changes ectopic pregnancy rate per couple compared with IUI (very low certainty).

1 finding from 1 review

Intra‐uterine insemination for unexplained subfertility 2020 · Cochrane Headline outcomes only
OR 6.48 [0.33, 127.09]
1 study · 211 participants
Very low

Ectopic pregnancy rate per couple · participants with unexplained subfertility

IUI in a natural cycle showed no clear difference in ectopic pregnancy rate per couple compared with TI or expectant management (low certainty).

2 findings from 1 review

Intra‐uterine insemination for unexplained subfertility 2020 · Cochrane Headline outcomes only
OR 5.3 [0.25, 111.26]
1 study · 342 participants
Low
Intra‐uterine insemination for unexplained subfertility 2020 · Cochrane Headline outcomes only
OR 5.06 [0.24, 1106.21]
1 study · 334 participants
Low

Ectopic pregnancy rate per couple · participants with unexplained subfertility

IUI in a stimulated cycle showed no clear difference in ectopic pregnancy rate per couple compared with TI or expectant management (low certainty).

2 findings from 1 review

Intra‐uterine insemination for unexplained subfertility 2020 · Cochrane Headline outcomes only
OR 3.06 [0.12, 76.95]
1 study · 100 participants
Low
Intra‐uterine insemination for unexplained subfertility 2020 · Cochrane Headline outcomes only
OR 9.28 [0.49, 174.6]
1 study · 201 participants
Low

Ectopic pregnancy rate per couple · intrauterine insemination (IUI) in women with infertility

Aromatase inhibitors showed no clear difference in ectopic pregnancy rate per couple compared with anti‐oestrogens (low certainty).

1 finding from 1 review

Ectopic pregnancy rate per couple · intrauterine insemination (IUI) in women with infertility

Gonadotropins with GnRH antagonist showed no clear difference in ectopic pregnancy rate per couple compared with gonadotropins alone (low certainty).

1 finding from 1 review

Ectopic pregnancy rate per couple · intrauterine insemination (IUI) in women with infertility

Gonadotropins showed no clear difference in ectopic pregnancy rate per couple compared with anti‐oestrogens (low certainty).

1 finding from 1 review