What do systematic reviews say?

Topical antibiotics with steroids vs topical antibiotics

It is very uncertain whether topical antibiotics with steroids changes ear pain (otalgia) or discomfort or local irritation compared with topical antibiotics alone (same antibiotics) (very low certainty).

• Topical antibiotics with steroids for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
  RR 0.98
  1 study · 105 participants
  Very low

Topical antibiotics vs placebo/no treatment

• Topical antibiotics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 35 participants
  Very low

Topical antibiotics with steroids vs placebo/no treatment

• Topical antibiotics with steroids for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 123 participants
  Very low

Antibiotics vs no treatment or placebo on top of topical antibiotics

The review found no eligible studies for this question.

• Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Antibiotics vs no treatment or placebo on top of topical antibiotics

It is very uncertain whether systemic antibiotics changes ear pain (otalgia) or discomfort or local irritation ‐ measured at 1… compared with no treatment or placebo on top of topical antibiotics (very low certainty).

• Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
  RR 1 [0.21, 4.72]
  1 study · 100 participants
  Very low

Antibiotics vs no treatment or placebo on top of topical antiseptics

The review found no eligible studies for this question.

• Systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Topical quinolone vs intramuscular gentamicin

• Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 60 participants
  Very low

Topical quinolone vs oral amoxicillin‐clavulanic acid combination

• Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 56 participants
  Very low

Topical quinolone vs quinolones

The review found no eligible studies for this question.

• Topical versus systemic antibiotics for chronic suppurative otitis media 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Intervention not reported

The review found no eligible studies for this question.

• Topical antibiotics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Quinolone vs aminoglycosides

• Topical antibiotics for chronic suppurative otitis media 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 308 participants
  Very low