Findings

What do systematic reviews say?

247 questions · 259 findings · 100 reviews

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No studies found 51 · 19.7%GRADE not reported 26 · 10%Very low 92 · 35.5%Low 59 · 22.8%Moderate 29 · 11.2%High 2 · 0.8%

Antidepressants vs any other pharmacological intervention

Depression response (early phase, < 5 weeks) · women of any age, with PND up to 12 months

1 finding from 1 review

Antidepressant treatment for postnatal depression 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Antidepressants vs any other pharmacological intervention

Depression remission · women of any age, with PND up to 12 months

It is very uncertain whether antidepressants changes depression remission (acute phase, 5 ≤ 12 weeks) compared with any other pharmacological intervention (very low certainty).

2 findings from 1 review

Antidepressant treatment for postnatal depression 2021 · Cochrane Headline outcomes only
RR 0.98 [0.68, 1.41]
Studies not reported
Very low
Antidepressant treatment for postnatal depression 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Antidepressants vs psychosocial interventions

Depression severity (acute phase, 5 ≤ 12 weeks) · women of any age, with PND up to 12 months

The review found no eligible studies for this question.

1 finding from 1 review

Antidepressant treatment for postnatal depression 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antidepressants vs any other pharmacological intervention

Depression response (acute phase, 5 ≤ 12 weeks) · women of any age, with PND up to 12 months

It is very uncertain whether antidepressants changes depression response (acute phase, 5 ≤ 12 weeks) compared with any other pharmacological intervention (very low certainty).

1 finding from 1 review

Antidepressant treatment for postnatal depression 2021 · Cochrane Headline outcomes only
RR 0.98 [0.76, 1.27]
Studies not reported
Very low

Alpha‐blockers vs placebo

Anxiety and depression · participants with chronic prostatitis/chronic pelvic pain syndrome

1 finding from 1 review

Pharmacological interventions for treating chronic prostatitis/chronic pelvic pain syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 232 participants
Low

Smart technology vs face‐to‐face/digital and/or written support

Anxiety and depression · COPD

1 finding from 1 review

Computer and mobile technology interventions for self‐management in chronic obstructive pulmonary disease 2017 · Cochrane Headline outcomes only
no estimate extracted
0 participants
GRADE not reported

Yoga vs psychosocial/educational interventions

Depression (short‐term) Self‐assessed questionnaires · women with diagnosed breast cancer

1 finding from 1 review

Yoga for improving health‐related quality of life, mental health and cancer‐related symptoms in women diagnosed with… 2017 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 226 participants
Moderate

Reflexology vs sham

Reduction in depression · chronic pain in MS

1 finding from 1 review

Non‐pharmacological interventions for chronic pain in multiple sclerosis 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 71 participants
Very low

Intervention not reported

Depression BSI Patients · patients and carers

1 finding from 1 review

Information interventions for orienting patients and their carers to cancer care facilities 2011 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 304 participants
Low

Hypnosis vs relaxation

Depression (short term) · Adults over 18 years of age with chronic orofacial pain (temporomandibular disorder (TMD))

Hypnosis led to lower depression (short term) compared with relaxation; GRADE not reported.

1 finding from 1 review

Psychosocial interventions for the management of chronic orofacial pain 2011 · Cochrane All outcomes
Short term
SMD -0.49 [-0.93, -0.04]
2 studies · 81 participants
GRADE not reported

Exercise vs usual care

Major depression · people with ESKD

Exercise may leads to lower major depression (median compared with usual care (low certainty).

1 finding from 1 review

Psychosocial interventions for preventing and treating depression in dialysis patients 2019 · Cochrane Headline outcomes only
RR 0.47 [0.27, 0.81]
3 studies · 108 participants
Low

Antidepressants vs psychological interventions

Depression response or remission (acute phase, 5 ≤ 12 weeks) · women of any age, with PND up to 12 months

The review found no eligible studies for this question.

1 finding from 1 review

Antidepressant treatment for postnatal depression 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Antidepressants vs psychosocial interventions

Depression response or remission (acute phase, 5 ≤ 12 weeks) · women of any age, with PND up to 12 months

The review found no eligible studies for this question.

1 finding from 1 review

Antidepressant treatment for postnatal depression 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Parent‐infant psychotherapy vs other (psychoeducational) parenting intervention: parent mental health and infant attachment

Parent mental health meta‐analysis: depression continuous data ‐ · participants with improving parental and infant mental health

1 finding from 1 review

Parent‐infant psychotherapy for improving parental and infant mental health 2015 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 160 participants
Low

Antidepressants vs psychological interventions

Depression severity (acute phase, 5 ≤ 12 weeks) · women of any age, with PND up to 12 months

1 finding from 1 review

Antidepressant treatment for postnatal depression 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Antidepressants vs any other pharmacological intervention

Depression severity (acute phase, 5 ≤ 12 weeks) · women of any age, with PND up to 12 months

1 finding from 1 review

Antidepressant treatment for postnatal depression 2021 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Very low

Summary of findings table ‐ Kappa‐opioid agonists vs placebo

Depression ‐ not measured · patients with chronic kidney disease (CKD) pruritus

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for pruritus in adult palliative care patients 2024 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Summary of findings table ‐ Ondansetron vs placebo

Depression ‐ not measured · patients with chronic kidney disease (CKD) pruritus

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for pruritus in adult palliative care patients 2024 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Montelukast vs placebo

Depression ‐ not measured · patients with chronic kidney disease (CKD) pruritus

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for pruritus in adult palliative care patients 2024 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Omega‐3 vs placebo

Depression ‐ not measured · patients with chronic kidney disease (CKD) pruritus

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for pruritus in adult palliative care patients 2024 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found