Findings

What do systematic reviews say?

7 questions · 7 findings · 3 reviews · Neonatal

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No studies found 0 · 0%GRADE not reported 2 · 28.6%Very low 2 · 28.6%Low 3 · 42.9%Moderate 0 · 0%High 0 · 0%

Fish oil lipid emulsion (LE) vs non‐fish oil LE

Mortality before hospital discharge · parenterally fed term and late preterm infants

It is very uncertain whether fish oil LE changes death before discharge compared with non‐fish oil LE (very low certainty).

1 finding from 1 review

Lipid emulsions for parenterally fed term and late preterm infants 2019 · Cochrane Headline outcomes only
RR 0.24 [0.03, 1.87]
2 studies · 40 participants
Very low

Fish oil lipid emulsion (LE) vs non‐fish oil LE

Mortality before hospital discharge · parenterally fed term and late preterm infants with surgical conditions

1 finding from 1 review

Lipid emulsions for parenterally fed term and late preterm infants 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 68 participants
GRADE not reported

Fish oil lipid emulsion (LE) vs non‐fish oil LE

Death of baby (up to discharge) · Parenterally fed preterm infants

Fish oil lipid emulsion (LE) showed no clear difference in death before discharge – MOFS‐LE vs S‐LE compared with non‐fish oil LE (low certainty).

1 finding from 1 review

Lipid emulsions for parenterally fed preterm infants 2019 · Cochrane Headline outcomes only
RR 1.24 [0.81, 1.9]
9 studies · 855 participants
Low

Fish oil lipid emulsion (LE) vs another fish oil LE

Death at hospital discharge · Parenterally fed preterm infants

Fish oil lipid emulsion (LE) showed no clear difference in death before discharge – MOFS‐LE vs MFS‐LE compared with another fish oil LE (low certainty).

1 finding from 1 review

Lipid emulsions for parenterally fed preterm infants 2019 · Cochrane Headline outcomes only
RR 1 [0.15, 6.64]
1 study · 60 participants
Low

Fish oil lipid emulsion (LE) vs non‐fish oil LE

Death at hospital discharge · parenterally fed preterm infants with surgical conditions

1 finding from 1 review

Lipid emulsions for parenterally fed preterm infants 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 19 participants
GRADE not reported

Fish oil lipid emulsion (LE) vs non‐fish oil LE

Death of baby (up to discharge) · parenterally fed preterm infants with cholestasis

It is very uncertain whether fish oil lipid emulsion (LE) changes death before discharge – MOFS‐LE vs S‐LE – Pure F‐LE vs IL compared with non‐fish oil LE (very low certainty).

1 finding from 1 review

Lipid emulsions for parenterally fed preterm infants 2019 · Cochrane Headline outcomes only
RR 0.24 [0.03, 1.87]
2 studies · 40 participants
Very low

Fish oil lipid emulsion (LE) vs S‐LE

Mortality before hospital discharge · Parenterally fed preterm infants

All fish oil containing LE showed no clear difference in death before discharge compared with S‐LE (low certainty).

1 finding from 1 review

Alternative lipid emulsions versus pure soy oil based lipid emulsions for parenterally fed preterm infants 2015 · Cochrane Headline outcomes only
RR 1.28 [0.69, 2.35]
5 studies · 399 participants
Low