Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

12 questions · 12 findings · 3 reviews · Neuromuscular

No studies found 3 · 25%GRADE not reported 1 · 8.3%Very low 3 · 25%Low 3 · 25%Moderate 1 · 8.3%High 1 · 8.3%

Corticosteroids vs control

Death or disability after 1 year · patients with Guillain‐Barré syndrome

Corticosteroid showed no clear difference in death or disability after 1 year compared with control (moderate certainty).

1 finding from 1 review

Brain‐derived neurotrophic factor vs placebo

Death or disability after 12 months · patients with Guillain‐Barré syndrome

It is very uncertain whether brain‐derived neurotrophic factor changes death or disability after 12 months compared with placebo (very low certainty).

1 finding from 1 review

Eculizumab vs placebo

Death or disability after 12 months In the absence of data at 12 months, we report the outcome at 6 months · adults with severe Guillain‐Barré syndrome (GBS disability score > 2), within 2 weeks form onset

It is very uncertain whether eculizumab changes death or disability after 12 months In the absence of data at 12… compared with placebo (very low certainty).

1 finding from 1 review