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What do systematic reviews say?

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Evidence found and GRADE certainty

8 questions · 8 findings · 4 reviews · Effective Practice and Organisation of Care

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 6 · 75%Low 0 · 0%Moderate 1 · 12.5%High 1 · 12.5%

Lay health worker‐ vs enhanced usual care

Adverse events ‐ death in past 12 months (RR > 1 denotes higher risk of death) · adult patients with alcohol dependence

It is very uncertain whether lay health worker‐led interventions changes adverse events ‐ death in past 12 months (RR > 1 denotes higher risk… compared with enhanced usual care (very low certainty).

1 finding from 1 review

Perinatal death review and audit as part of an intervention package including an educational outreach visit and morbidity/mortality conferences vs no intervention

Proportion of perinatal deaths related to suboptimal carec (at months 12–26) · births

It is very uncertain whether perinatal death review and audit as part of an intervention package… changes proportion of perinatal deaths related to suboptimal carec (at… compared with no intervention (very low certainty).

1 finding from 1 review

Lay health worker‐led interventions for adult patients with harmful or hazardous alcohol or substance use vs enhanced usual care

Adverse events ‐ death in past 12 months (RR > 1 denotes higher risk of death) · adult patients with harmful or hazardous alcohol or substance use

It is very uncertain whether lay health worker‐led interventions for adult patients with harmful… changes adverse events ‐ deaths (RR < 1 denotes lower risk) compared with enhanced usual care (very low certainty).

1 finding from 1 review

Lay health worker‐ vs specialist‐led care

Adverse events ‐ death from suicide during intervention (RR > 1 denotes greater risk)Â · people with severe mental disorders

It is very uncertain whether lay health worker‐ changes adverse events ‐ death from suicide during intervention (RR > 1… compared with specialist‐led care (very low certainty).

1 finding from 1 review

Primary‐level worker‐led collaborative care vs usual care

Adverse events ‐ death · adults with common mental disorders

It is very uncertain whether primary‐level worker‐led collaborative care changes adverse events ‐ death compared with usual care (very low certainty).

1 finding from 1 review

Intervention not reported

Intrapartum and neonatal deaths · nurses, midwives, physicians

The intervention showed no clear difference in intrapartum and neonatal deaths (high certainty).

1 finding from 1 review

Intervention not reported

Patient outcome: death, disability or dependency at 90 days · health professionals providing care to patients with stroke

The intervention showed no clear difference in patient outcome: death, disability or dependency at 90 days (moderate certainty).

1 finding from 1 review