Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

95 questions · 96 findings · 37 reviews

No studies found 24 · 25%GRADE not reported 1 · 1%Very low 30 · 31.3%Low 21 · 21.9%Moderate 12 · 12.5%High 8 · 8.3%

Intermittent ICS vs placebo

Exacerbations requiring oral corticosteroids ‐ School‐age children · School‐aged children and adults

Intermittent ICS showed no clear difference in exacerbations requiring oral corticosteroids ‐ School‐age children compared with placebo (low certainty).

1 finding from 1 review

Formoterol vs short‐acting beta2‐agonist

Exacerbations requiring oral corticosteroids ‐ adults · people with asthma

Formoterol probably leads to lower patients with an exacerbation requiring a course of oral… compared with short‐acting beta2‐agonist (moderate certainty).

1 finding from 1 review

Intervention not reported

Anti‐thymocyte globulin plus glucocorticosteroids (1 RCT; 37 participants) · adults undergoing liver transplantation

It is very uncertain whether the intervention changes anti‐thymocyte globulin plus glucocorticosteroids (1 RCT; 37… (very low certainty).

1 finding from 1 review

Intervention not reported

Anti‐thymocyte globulin plus glucocorticosteroids (1 RCT; 93 participants) · adults undergoing liver transplantation

It is very uncertain whether the intervention changes anti‐thymocyte globulin plus glucocorticosteroids (1 RCT; 93… (very low certainty).

1 finding from 1 review

Intervention not reported

Number of participants requiring oral corticosteroids over the study period · Adults from minority groups with doctor diagnosed asthma

It is very uncertain whether the intervention changes number of participants requiring oral corticosteroids over the study… (very low certainty).

1 finding from 1 review