Methotrexate probably leads to higher proportion of patients maintaining clinical remission compared with placebo (moderate certainty).
It is very uncertain whether metronidazole changes clinical remission compared with budesonide enema (very low certainty).
It is very uncertain whether methotrexate changes proportion of patients achieved clinical remission compared with 6‐mercaptopurine (very low certainty).
It is very uncertain whether methotrexate changes proportion of patients achieved clinical remission compared with 5‐aminosalicylic acid (5‐ASA) (very low certainty).
It is very uncertain whether methotrexate changes proportion of patients maintaining clinical remission compared with 6‐mercaptopurine (very low certainty).
The review found no eligible studies for this question.
Tacrolimus showed no clear difference in clinical remission compared with beclometasone (low certainty).
It is very uncertain whether ciprofloxacin changes clinical remission compared with metronidazole (very low certainty).
Azathioprine or 6‐mercaptopurine showed no clear difference in clinical remission1 compared with methotrexate (low certainty).
The review found no eligible studies for this question.