Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

10 questions · 11 findings · 3 reviews · Gynaecology and Fertility

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 3 · 27.3%Low 7 · 63.6%Moderate 1 · 9.1%High 0 · 0%

Antioestrogen vs antioestrogen

Clinical pregnancy rate · ovulation induction in polycystic ovarian syndrome

It is very uncertain whether antioestrogen changes clomiphene citrate plus tamoxifen versus clomiphene citrate ‐… compared with antioestrogen (very low certainty).

2 findings from 1 review

Transdermal oestrogens vs oral oestrogens

Clinical pregnancy rate · women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes

Transdermal oestrogens showed no clear difference in clinical pregnancy rate compared with oral oestrogens (low certainty).

1 finding from 1 review

Antioestrogen plus medical adjunct vs antioestrogen

Clinical pregnancy · ovulation induction in polycystic ovarian syndrome

Antioestrogen plus medical adjunct showed no clear difference in clomiphene citrate plus bromocriptine versus clomiphene citrate ‐… compared with antioestrogen alone (low certainty).

1 finding from 1 review

Gonadotrophins with anti‐oestrogens vs gonadotropins alone

Clinical pregnancy rate · intrauterine insemination (IUI) in women with infertility

It is very uncertain whether gonadotrophins with anti‐oestrogens changes clinical pregnancy rate per couple compared with gonadotropins alone (very low certainty).

1 finding from 1 review

Aromatase inhibitors with gonadotropins vs anti‐oestrogens with gonadotropins

Clinical pregnancy rate · intrauterine insemination (IUI) in women with infertility

It is very uncertain whether aromatase inhibitors with gonadotropins changes clinical pregnancy rate per couple compared with anti‐oestrogens with gonadotropins (very low certainty).

1 finding from 1 review

Intervention not reported

Clinical pregnancy ‐ Early versus late clomiphene citrate · ovulation induction in polycystic ovarian syndrome

The intervention may leads to higher clinical pregnancy ‐ Early versus late clomiphene citrate (low certainty).

1 finding from 1 review

Intervention not reported

Clinical pregnancy ‐ Clomiphene citrate 5 days versus clomiphene citrate 10 days · ovulation induction in polycystic ovarian syndrome

The intervention may leads to lower clinical pregnancy ‐ Clomiphene citrate 5 days versus clomiphene… (low certainty).

1 finding from 1 review