Clinical attachment level (CAL) · People with maxillary palatally displaced (impacted) canines, unilateral or bilateral (children/adolescents; mean ages 14.2 to 17.5 years)
Open surgical exposure showed no clear difference in gum health: clinical attachment level (CAL) compared with closed surgical exposure (low certainty).
1 finding from 1 review
Attachment change · Adults with chronic periodontitis
Occlusal adjustment as an adjunct to surgical periodontal therapy led to higher clinical attachment level change (mean gain, mm) compared with surgical periodontal therapy alone (no occlusal adjustment); GRADE not reported.
1 finding from 1 review
Attachment change · Adults with chronic periodontitis
Occlusal adjustment as an adjunct to non-surgical periodontal therapy led to higher clinical attachment level change (mean gain, mm) compared with non-surgical periodontal therapy alone (no occlusal adjustment); GRADE not reported.
1 finding from 1 review
Attachment change · Adults (> 18 years) with a clinical diagnosis of periodontitis, receiving active (non-surgical anti-infective) treatment
Adjunctive antimicrobial photodynamic therapy (aPDT) applied after… led to higher change in clinical attachment level (CAL) compared with subgingival instrumentation (SI) alone (hand or power-driven, or…; GRADE not reported.
2 findings from 1 review
Clinical attachment level (CAL) · Adults with aggressive periodontitis
Doxycycline + SRP showed no clear difference in clinical attachment level (CAL) compared with metronidazole + SRP; GRADE not reported.
3 findings from 1 review
MD 0.34 [-0.08, 0.76]
3 studies · 75 participants
GRADE not reported
MD 1.10 [0.36, 1.84]
1 study · 27 participants
Very low
MD -0.12 [-0.72, 0.49]
2 studies · 49 participants
GRADE not reported
Clinical attachment level (CAL) · Adults with aggressive periodontitis
It is very uncertain whether doxycycline + SRP changes clinical attachment level (CAL) compared with SRP (very low certainty).
3 findings from 1 review
MD -0.80 [-1.49, -0.11]
1 study · 22 participants
Very low
MD -0.61 [-1.14, -0.08]
3 studies · 65 participants
GRADE not reported
MD 0.15 [-0.53, 0.83]
2 studies · 43 participants
GRADE not reported
Clinical attachment level (CAL) · Adults with aggressive periodontitis
Amoxicillin + metronidazole + SRP showed no clear difference in clinical attachment level (CAL) compared with clarithromycin + SRP; GRADE not reported.
2 findings from 1 review
Clinical attachment level (CAL) · Adults with aggressive periodontitis
It is very uncertain whether clindamycin + SRP changes clinical attachment level (CAL) compared with doxycycline + SRP (very low certainty).
3 findings from 1 review
MD -0.90 [-1.62, -0.18]
1 study · 23 participants
Very low
MD -0.40 [-1.15, 0.35]
1 study · 23 participants
GRADE not reported
MD 0.50 [-0.26, 1.26]
1 study · 23 participants
GRADE not reported
Clinical attachment level (CAL) · Adults with aggressive periodontitis
Tetracycline + SRP led to lower clinical attachment level (CAL) compared with SRP; GRADE not reported.
3 findings from 1 review
MD -1.90 [-2.17, -1.63]
1 study · 26 participants
GRADE not reported
MD -2.30 [-2.50, -2.10]
1 study · 26 participants
Very low
MD -0.92 [-2.38, 0.54]
2 studies · 64 participants
GRADE not reported
Clinical attachment level (CAL) · Adults with aggressive periodontitis
Clindamycin + SRP led to lower clinical attachment level (CAL) compared with SRP; GRADE not reported.
3 findings from 1 review
MD -1.30 [-2.14, -0.46]
1 study · 21 participants
GRADE not reported
MD 0.40 [-0.35, 1.15]
1 study · 21 participants
GRADE not reported
MD -1.70 [-2.40, -1.00]
1 study · 21 participants
Very low
Clinical attachment level (CAL) · Adults with aggressive periodontitis
Doxycycline + SRP showed no clear difference in clinical attachment level (CAL) compared with amoxicillin + metronidazole + SRP; GRADE not reported.
2 findings from 1 review
Clinical attachment level (CAL) · Adults with periodontitis (chronic and aggressive)
Clarithromycin + SRP led to lower clinical attachment level (CAL) compared with SRP; GRADE not reported.
2 findings from 1 review
Clinical attachment level (CAL) · Adults with periodontitis (chronic and aggressive)
Metronidazole + SRP showed no clear difference in clinical attachment level (CAL) compared with amoxicillin + metronidazole + SRP; GRADE not reported.
2 findings from 1 review
Clinical attachment level (CAL) · Adults with chronic periodontitis
Cefixime + SRP showed no clear difference in clinical attachment level (CAL) compared with SRP; GRADE not reported.
1 finding from 1 review
Clinical attachment level (CAL) · Adults with chronic periodontitis
Amoxicillin + clavulanate + SRP showed no clear difference in clinical attachment level (CAL) compared with SRP; GRADE not reported.
3 findings from 1 review
MD 0.10 [-0.45, 0.65]
1 study · 21 participants
GRADE not reported
MD 0.10 [-0.51, 0.71]
1 study · 21 participants
Very low
MD 0.10 [-0.43, 0.63]
1 study · 21 participants
GRADE not reported
Clinical attachment level (CAL) · Adults with aggressive periodontitis
Clindamycin + SRP showed no clear difference in clinical attachment level (CAL) compared with metronidazole + SRP; GRADE not reported.
3 findings from 1 review
MD 0.40 [-0.22, 1.02]
1 study · 26 participants
GRADE not reported
MD 0.20 [-0.55, 0.95]
1 study · 26 participants
Very low
MD 0.10 [-0.60, 0.80]
1 study · 26 participants
GRADE not reported
Clinical attachment level (CAL) · Adults with periodontitis (chronic and aggressive)
It is very uncertain whether amoxicillin + metronidazole + SRP changes clinical attachment level (CAL) compared with SRP (very low certainty).
3 findings from 1 review
MD -0.47 [-0.90, -0.05]
2 studies · 389 participants
Very low
MD -0.21 [-0.41, -0.01]
13 studies · 501 participants
GRADE not reported
MD -0.04 [-0.35, 0.26]
6 studies · 215 participants
GRADE not reported
Clinical attachment level (CAL) · Adults with periodontitis (chronic and aggressive)
It is very uncertain whether azithromycin + SRP changes clinical attachment level (CAL) compared with SRP (very low certainty).
3 findings from 1 review
MD -0.59 [-1.27, 0.08]
2 studies · 110 participants
Very low
MD -0.43 [-0.77, -0.10]
7 studies · 258 participants
GRADE not reported
MD -0.51 [-0.83, -0.19]
6 studies · 216 participants
GRADE not reported
Clinical attachment level (CAL) · Adults with chronic periodontitis
Moxifloxacin + SRP led to lower clinical attachment level (CAL) compared with SRP; GRADE not reported.
2 findings from 1 review
Clinical attachment level (CAL) · Adults with periodontitis (chronic and aggressive)
Metronidazole + SRP showed no clear difference in clinical attachment level (CAL) compared with SRP; GRADE not reported.
3 findings from 1 review
MD 0.04 [-0.43, 0.50]
4 studies · 108 participants
GRADE not reported
MD -1.12 [-2.24, 0.00]
3 studies · 71 participants
Very low
MD -0.49 [-1.29, 0.31]
4 studies · 94 participants
GRADE not reported