What do systematic reviews say?

Pulmonary rehabilitation vs no pulmonary rehabilitation

• Pulmonary rehabilitation for interstitial lung disease 2021 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 194 participants
  Moderate

Pulmonary rehabilitation vs no pulmonary rehabilitation

• Pulmonary rehabilitation for interstitial lung disease 2021 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 89 participants
  Low

Pulmonary rehabilitation vs no pulmonary rehabilitation

• Pulmonary rehabilitation for interstitial lung disease 2021 · Cochrane Headline outcomes only
  no estimate extracted
  11 studies · 478 participants
  Moderate

Pulmonary rehabilitation vs no pulmonary rehabilitation

• Pulmonary rehabilitation for interstitial lung disease 2021 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 240 participants
  Low

Micropulse vs continuous‐wave cyclophotocoagulation

The review found no eligible studies for this question.

• Cyclodestructive procedures for refractory glaucoma 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Selective serotonin reuptake inhibitors vs placebo

• Pharmacological interventions for the treatment of depression in chronic obstructive pulmonary disease 2018 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 148 participants
  Very low

Long‐acting beta2‐agonist plus tiotropium vs tiotropium

• Long‐acting beta₂‐agonist in addition to tiotropium versus either tiotropium or long‐acting beta₂‐agonist alone for… 2015 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 6709 participants
  Moderate

Long‐acting beta2‐agonist plus tiotropium vs long‐acting beta2‐agonist alone

• Long‐acting beta₂‐agonist in addition to tiotropium versus either tiotropium or long‐acting beta₂‐agonist alone for… 2015 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 3378 participants
  Moderate

Psychological therapies vs no intervention

• Psychological therapies for the treatment of depression in chronic obstructive pulmonary disease 2019 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 348 participants
  Very low

Inhaled corticosteroids vs placebo

• Inhaled corticosteroids versus placebo for stable chronic obstructive pulmonary disease 2023 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 2507 participants
  Moderate

Psychological therapies vs education

• Psychological therapies for the treatment of depression in chronic obstructive pulmonary disease 2019 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 460 participants
  Very low

Tricylic antidepressant vs placebo

• Pharmacological interventions for the treatment of depression in chronic obstructive pulmonary disease 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 30 participants
  Very low

Non‐invasive ventilation during exercise training vs exercise training alone or exercise training with sham non‐invasive ventilation

• Non‐invasive ventilation during exercise training for people with chronic obstructive pulmonary disease 2014 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 48 participants
  Moderate

Summary of findings table ‐ Cannabis vs placebo

• Cannabis and cannabinoids for symptomatic treatment for people with multiple sclerosis 2022 · Cochrane Headline outcomes only
  no estimate extracted
  8 studies · 1942 participants
  Low

Summary of Findings Table ‐ Chronic non‐invasive ventilation vs standard treatment following a severe exacerbation

• Chronic non‐invasive ventilation for chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 219 participants
  Very low
• Chronic non‐invasive ventilation for chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 164 participants
  Very low

Summary of Findings Table ‐ Chronic non‐invasive ventilation vs usual care

• Chronic non‐invasive ventilation for chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
  no estimate extracted
  5 studies · 259 participants
  Very low
• Chronic non‐invasive ventilation for chronic obstructive pulmonary disease 2021 · Cochrane Headline outcomes only
  no estimate extracted
  4 studies · 200 participants
  Very low

Beclometasone/LABA vs LABA

• Beclometasone for chronic obstructive pulmonary disease 2013 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 465 participants
  Moderate

Summary of findings: Inhaled antibiotics vs IV antibiotics

• Inhaled antibiotics for pulmonary exacerbations in cystic fibrosis 2022 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 18 participants
  Very low

LABA/LAMA vs LABA plus inhaled corticosteroid (ICS)

Long‐acting muscarinic antagonist (LAMA) plus long‐acting… showed no clear difference in quality of life as measured by SGRQ total score change from baseline… compared with LABA plus inhaled corticosteroid (ICS) (moderate certainty).

• Long‐acting muscarinic antagonist (LAMA) plus long‐acting beta‐agonist (LABA) versus LABA plus inhaled corticosteroid… 2023 · Cochrane Headline outcomes only
  no estimate extracted
  9 studies · 14437 participants
  Moderate

Benralizumab 100 mg vs placebo

• Anti‐IL‐5 therapies for chronic obstructive pulmonary disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 1433 participants
  High