Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3 questions · 3 findings · 1 reviews · Periodontology

No studies found 0 · 0%GRADE not reported 1 · 33.3%Very low 0 · 0%Low 2 · 66.7%Moderate 0 · 0%High 0 · 0%

Enamel matrix derivative (EMD; Emdogain) vs Various bone grafting (BG) procedures (animal-derived or synthetic bone / bioactive ceramic filler)

Change in probing attachment level (PAL) · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…
1 finding from 1 review

Enamel matrix derivative (EMD; Emdogain) vs placebo or control

Change in probing attachment level (PAL) · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…

Enamel matrix derivative (EMD; Emdogain) may leads to higher change in probing attachment level (PAL) compared with placebo or control (same surgical or non-surgical intervention… (low certainty).

1 finding from 1 review

Enamel matrix derivative (EMD; Emdogain) vs Guided tissue regeneration (GTR) with barriers

Change in probing attachment level (PAL) · Patients affected by chronic, aggressive, or early onset periodontitis, with intrabony defects having an intrabony component of at least 3…

Enamel matrix derivative (EMD; Emdogain) showed no clear difference in change in probing attachment level (PAL) compared with guided tissue regeneration (GTR) with barriers (low certainty).

1 finding from 1 review