Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

7 questions · 12 findings · 3 reviews

No studies found 0 · 0%GRADE not reported 7 · 58.3%Very low 5 · 41.7%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Occlusal adjustment as an adjunct to surgical periodontal therapy vs Surgical periodontal therapy alone (no occlusal adjustment)

Attachment change · Adults with chronic periodontitis

Occlusal adjustment as an adjunct to surgical periodontal therapy led to higher clinical attachment level change (mean gain, mm) compared with surgical periodontal therapy alone (no occlusal adjustment); GRADE not reported.

1 finding from 1 review

Occlusal adjustment as an adjunct to non-surgical periodontal therapy vs Non-surgical periodontal therapy alone (no occlusal adjustment)

Attachment change · Adults with chronic periodontitis

Occlusal adjustment as an adjunct to non-surgical periodontal therapy led to higher clinical attachment level change (mean gain, mm) compared with non-surgical periodontal therapy alone (no occlusal adjustment); GRADE not reported.

1 finding from 1 review

Adjunctive antimicrobial photodynamic therapy (aPDT) applied after subgingival instrumentation (SI) vs Subgingival instrumentation (SI) alone (hand or power-driven, or both), or SI plus placebo/sham aPDT

Attachment change · Adults (> 18 years) with a clinical diagnosis of periodontitis, receiving active (non-surgical anti-infective) treatment

Adjunctive antimicrobial photodynamic therapy (aPDT) applied after… led to higher change in clinical attachment level (CAL) compared with subgingival instrumentation (SI) alone (hand or power-driven, or…; GRADE not reported.

2 findings from 1 review

Autologous platelet concentrates (APC) + guided tissue regeneration (GTR) vs GTR (guided tissue regeneration) alone

Attachment change · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender

It is very uncertain whether autologous platelet concentrates (APC) + guided tissue regeneration… changes change in clinical attachment level (CAL) (mm) compared with GTR (guided tissue regeneration) alone (very low certainty).

3 findings from 1 review

Autologous platelet concentrates (APC) + enamel matrix derivative (EMD) vs EMD (enamel matrix derivative) alone

Attachment change · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender

It is very uncertain whether autologous platelet concentrates (APC) + enamel matrix derivative… changes change in clinical attachment level (CAL) (mm) compared with EMD (enamel matrix derivative) alone (very low certainty).

1 finding from 1 review

Autologous platelet concentrates (APC) + open flap debridement (OFD) + bone graft (BG) vs OFD + BG (open flap debridement + bone graft)

Attachment change · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender

It is very uncertain whether autologous platelet concentrates (APC) + open flap debridement (OFD)… changes change in clinical attachment level (CAL) (mm) compared with OFD + BG (open flap debridement + bone graft) (very low certainty).

3 findings from 1 review

Autologous platelet concentrates (APC) + open flap debridement (OFD) vs Open flap debridement (access flap surgery)

Attachment change · Patients affected by infrabony defects requiring surgical treatment, regardless of their age or gender

It is very uncertain whether autologous platelet concentrates (APC) + open flap debridement (OFD) changes change in clinical attachment level (CAL) (mm) compared with OFD (open flap debridement) alone (very low certainty).

1 finding from 1 review