Findings

What do systematic reviews say?

2 questions · 2 findings · 2 reviews · Hypertension

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 50%Moderate 1 · 50%High 0 · 0%

Antihypertensive drug therapy vs control

Cerebrovascular mortality + morbidity · adults aged 18‐59 years with primary hypertension (mild to moderate systolic or diastolic hypertension)

Antihypertensive drug therapy may leads to lower cerebrovascular mortality + morbidity compared with control (low certainty).

1 finding from 1 review

Pharmacotherapy for hypertension in adults aged 18 to 59 years 2017 · Cochrane Headline outcomes only
RR 0.46 [0.34, 0.64]
6 studies · 17278 participants
Low

Any antihypertensive drug vs placebo or no treatment

Cerebrovascular mortality + morbidity · adults 60 years or older with primary hypertension

Antihypertensive drug probably leads to lower cerebrovascular mortality and morbidity Mean duration of 3.7 years compared with placebo or no treatment (moderate certainty).

1 finding from 1 review

Pharmacotherapy for hypertension in adults 60 years or older 2019 · Cochrane Headline outcomes only
RR 0.66 [0.59, 0.74]
13 studies · 26042 participants
Moderate