Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

24 questions · 30 findings · 5 reviews

No studies found 0 · 0%GRADE not reported 28 · 93.3%Very low 0 · 0%Low 0 · 0%Moderate 2 · 6.7%High 0 · 0%

Fluoride in rinse vs Fluoride in dentifrice

Caries increment, surface index D(M)FS · Children or adolescents

The illustrative network meta-regression estimated an SMD for caries increment for fluoride in rinse versus fluoride in dentifrice across randomization year; the review did not state whether the difference was significant and certainty was not graded.

1 finding from 1 review

Fluoride in rinse vs no treatment

Caries increment, surface index D(M)FS · Children or adolescents

In the illustrative network meta-regression the SMD for caries increment differed between fluoride in rinse and no treatment at every displayed randomization year; certainty was not graded.

1 finding from 1 review

Fluoride in rinse vs placebo

Caries increment, surface index D(M)FS · Children or adolescents

In the illustrative network meta-regression the SMD for caries increment differed between fluoride in rinse and placebo at randomization years 1954 to 1990; certainty was not graded.

1 finding from 1 review

Fluoride mouthrinse (0.05-0.32% sodium fluoride or amine fluoride) added to daily fluoride toothpaste vs Fluoride mouthrinse

Caries increment on permanent tooth surfaces (D(M)FS), prevented fraction · Children and adolescents aged 16 years or less
1 finding from 1 review

Fluoride gel (topically applied; operator- or self-applied; any fluoride agent/concentration; frequency at least once a year) vs Fluoride mouthrinse

Caries increment in permanent teeth · Children and adolescents aged 16 years or less
1 finding from 1 review

Fluoride mouthrinse (0.05-0.32% sodium fluoride or amine fluoride) added to daily fluoride toothpaste vs Fluoride toothpaste alone

Caries increment on permanent tooth surfaces (D(M)FS), prevented fraction · Children and adolescents aged 16 years or less
1 finding from 1 review

Topical fluoride therapy (toothpaste, mouthrinse, gel or varnish; any fluoride agent/concentration; frequency at least once a year) vs placebo or no treatment

Caries increment on permanent whole teeth (D(M)FT), prevented fraction · Children and adolescents aged 16 years or younger (permanent dentition)
7 findings from 1 review
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Fluoride gel (topically applied; operator- or self-applied; any fluoride agent/concentration; frequency at least once a year) vs Fluoride in rinse

Caries increment, surface index D(M)FS · Children or adolescents

The illustrative network meta-regression estimated an SMD for caries increment for fluoride in gel versus fluoride in rinse across randomization year; the review did not state whether the difference was significant and certainty was not graded.

1 finding from 1 review