Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

5 questions · 5 findings · 1 reviews · Oral Health

No studies found 0 · 0%GRADE not reported 3 · 60%Very low 1 · 20%Low 1 · 20%Moderate 0 · 0%High 0 · 0%

Caries in upper primary incisors vs Reference (other primary tooth locations / caries-free)

Caries development in permanent teeth · School children and adolescents (6-18 years) followed from primary dentition (baseline examination before 72 months of age)

Caries in upper primary incisors has the lowest tooth-specific predictive value for permanent-teeth caries (RR 1.6; single study; not GRADE-rated).

1 finding from 1 review

Caries in first and second primary molars vs Reference (other primary tooth locations / caries-free)

Caries development in permanent teeth · School children and adolescents (6-18 years) followed from primary dentition (baseline examination before 72 months of age)

Caries in the first and second primary molars is the strongest tooth-specific predictor of caries in permanent teeth (RR 3.4; single study; not GRADE-rated).

1 finding from 1 review

Early childhood caries (ECC) vs Caries-free primary dentition

Caries development in permanent teeth · School children and adolescents (6-18 years) followed from primary dentition (baseline examination before 72 months of age)

Early childhood caries increases the likelihood of caries in permanent teeth roughly three-fold, but the certainty of evidence is very low (OR 3.22, 95% CI 2.80 to 3.71).

1 finding from 1 review

Male sex (boys) vs Female sex

Caries development in permanent teeth · School children and adolescents (6-18 years) followed from primary dentition (baseline examination before 72 months of age)

Gender is not associated with caries development in permanent teeth (OR 0.86, 95% CI 0.71 to 1.02; low certainty).

1 finding from 1 review

Unfavourable oral hygiene and dietary habits (frequent sweet/sugar consumption; low toothbrushing frequency in early childhood) vs Favourable oral hygiene and dietary habits

Caries development in permanent teeth · School children and adolescents (6-18 years) followed from primary dentition (baseline examination before 72 months of age)

Early-childhood oral hygiene and dietary habits show inconsistent associations with permanent-teeth caries, often losing significance after adjustment for past caries (2 studies; not pooled; not GRADE-rated).

1 finding from 1 review