Findings

What do systematic reviews say?

7 questions · 7 findings · 3 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 28.6%Low 2 · 28.6%Moderate 1 · 14.3%High 2 · 28.6%

Vaginal PGE₂ vs placebo or expectant management

Caesarean section · patients with induction of labour at term

Vaginal PGE₂ showed no clear difference in caesarean section compared with placebo or expectant management (low certainty).

1 finding from 1 review

Pharmacological and mechanical interventions for labour induction in outpatient settings 2017 · Cochrane Headline outcomes only
RR 0.8 [0.49, 1.31]
4 studies · 288 participants
Low

Vaginal PGE2 pessary vs vaginal PGE2

Caesarean section · women with a previous caesarean section, a live singleton fetus (37‐42 weeks of gestation) in cephalic presentation and a reactive…

It is very uncertain whether vaginal PGE2 pessary changes caesarean section compared with vaginal PGE2 tablet (very low certainty).

1 finding from 1 review

Methods of term labour induction for women with a previous caesarean section 2017 · Cochrane Headline outcomes only
RR 1.09 [0.74, 1.6]
1 study · 200 participants
Very low

Vaginal PGE2 vs intravenous (IV) oxytocin

Caesarean section · women with one previous lower segment caesarean section and requiring labour induction due to prolonged pregnancy or pre‐eclampsia,…

Vaginal PGE2 showed no clear difference in caesarean section compared with intravenous (IV) oxytocin (low certainty).

1 finding from 1 review

Methods of term labour induction for women with a previous caesarean section 2017 · Cochrane Headline outcomes only
RR 0.67 [0.22, 2.03]
1 study · 42 participants
Low

PGE2 vs placebo or no treatment

Caesarean section · patients with induction of labour at term

PGE2 showed no clear difference in caesarean section compared with placebo or no treatment (high certainty).

1 finding from 1 review

Vaginal prostaglandin (PGE2 and PGF2a) for induction of labour at term 2014 · Cochrane Headline outcomes only
RR 0.91 [0.81, 1.02]
36 studies · 6599 participants
High

(4.1) PGE2 gel vs PGE2 tablet (all women)

Caesarean section · patients with induction of labour at term

(4.1) PGE2 gel showed no clear difference in caesarean section compared with PGE2 tablet (all women) (high certainty).

1 finding from 1 review

Vaginal prostaglandin (PGE2 and PGF2a) for induction of labour at term 2014 · Cochrane Headline outcomes only
RR 0.91 [0.72, 1.17]
6 studies · 1046 participants
High

(7.1) PGE2 (controlled release) vs all PGE2 delivery systems (all women)

Caesarean section · patients with induction of labour at term

(7.1) PGE2 (controlled release) showed no clear difference in caesarean section compared with all PGE2 delivery systems (all women) (moderate certainty).

1 finding from 1 review

Vaginal prostaglandin (PGE2 and PGF2a) for induction of labour at term 2014 · Cochrane Headline outcomes only
RR 1.02 [0.82, 1.26]
11 studies · 1262 participants
Moderate

Double‐balloon catheter vs vaginal PGE2

Caesarean section · women with a previous caesarean section (subgroup of all women in the study) with intact fetal membranes, cephalic position and…

It is very uncertain whether double‐balloon catheter changes caesarean section compared with vaginal PGE2 (very low certainty).

1 finding from 1 review

Methods of term labour induction for women with a previous caesarean section 2017 · Cochrane Headline outcomes only
RR 0.97 [0.41, 2.32]
1 study · 16 participants
Very low