Pharmacological interventions vs placebo
Adverse events (control ‐ placebo) · young people
2 findings from 1 review
- no estimate extracted1 study · 207 participantsVery low
- no estimate extracted1 study · 211 participantsVery low
Findings
What do systematic reviews say?
4 questions · 6 findings · 2 reviews · Tobacco Addiction
No studies found 0 · 0%GRADE not reported 0 · 0%Very low 4 · 66.7%Low 0 · 0%Moderate 1 · 16.7%High 1 · 16.7%
Pharmacological interventions vs placebo
Smoking cessation · young people
It is very uncertain whether pharmacological interventions changes bupropion vs placebo Smoking cessation compared with placebo (very low certainty).
2 findings from 1 review
- RR 1.49 [0.55, 4.02]1 study · 207 participantsVery low
- RR 1.05 [0.41, 2.69]1 study · 211 participantsVery low
Intervention not reported
Bupropion · adults (aged ≥ 18 years) who smoked cigarettes Components: components of pharmacological and e‐cigarette (EC) interventions for smoking…
The intervention showed no clear difference in bupropion (moderate certainty).
1 finding from 1 review
- Pharmacological and electronic cigarette interventions for smoking cessation in adults: component network meta‐analyses 2023 · Cochrane Headline outcomes onlyOR 1.35 [0.97, 1.92]22 studies · 7231 participantsModerate
Intervention not reported
Bupropion · adults (aged ≥ 18 years) who smoked cigarettes Components: components of pharmacological and e‐cigarette (EC) interventions for smoking…
The intervention leads to higher bupropion (high certainty).
1 finding from 1 review
- Pharmacological and electronic cigarette interventions for smoking cessation in adults: component network meta‐analyses 2023 · Cochrane Headline outcomes onlyOR 1.43 [1.26, 1.62]71 studies · 14759 participantsHigh