What do systematic reviews say?

Oral misoprostol vs vaginal misoprostol

The review found no eligible studies for this question.

• Medical methods for first trimester abortion 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found
• Medical methods for first trimester abortion 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Sublingual misoprostol vs vaginal misoprostol

The review found no eligible studies for this question.

• Medical methods for first trimester abortion 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Sublingual misoprostol vs vaginal misoprostol

It is very uncertain whether sublingual misoprostol alone changes blood transfusion compared with vaginal misoprostol alone (very low certainty).

• Medical methods for first trimester abortion 2022 · Cochrane Headline outcomes only
  RR 5 [0.24, 102.96]
  1 study · 220 participants
  Very low

Misoprostol 800 µg plus mifepristone 200 mg vs mifepristone (200 mg) plus prostaglandin

The review found no eligible studies for this question.

• Medical methods for first trimester abortion 2022 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Misoprostol vs placebo to reduce blood loss during myomectomy

Misoprostol showed no clear difference in need for blood transfusion Number of participants who received blood… compared with placebo to reduce blood loss during myomectomy (low certainty).

• Interventions to reduce haemorrhage during myomectomy for fibroids 2014 · Cochrane Headline outcomes only
  OR 0.36 [0.05, 2.5]
  2 studies · 89 participants
  Low

Advance misoprostol distribution/provision to pregnant women for postpartum self‐administration vs usual care

• Advance misoprostol distribution to pregnant women for preventing and treating postpartum haemorrhage 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 299 participants
  Very low

Intrauterine balloon tamponade plus normal care (misoprostol) vs normal care (misoprostol)

It is very uncertain whether intrauterine balloon tamponade plus normal care (misoprostol) changes blood transfusion (red cell or whole blood) compared with normal care (misoprostol) (very low certainty).

• Mechanical and surgical interventions for treating primary postpartum haemorrhage 2020 · Cochrane Headline outcomes only
  RR 1.49 [0.88, 2.51]
  1 study · 116 participants
  Very low