Cochrane · systematic review · CD009336
Advance misoprostol distribution to pregnant women for preventing and treating postpartum haemorrhage
Oladapo, OT, Blum, J, Abalos, E, et al. · Cochrane Database of Systematic Reviews · 2020 · Cochrane Library
Pregnancy and ChildbirthAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
7
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 1 · 14.3%Very low 6 · 85.7%Low 0 · 0%Moderate 0 · 0%High 0 · 0%
Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.
Questions and results
Advance misoprostol distribution/provision to pregnant women for postpartum self‐administration versus usual (or standard) care for prevention of postpartum haemorrhage
Population: women in the third stage of labour
| Outcome | Effect | Evidence | Status / GRADE |
|---|---|---|---|
Severe postpartum haemorrhage Advance misoprostol distribution/provision to pregnant women for postpartum self‐administration vs usual (or standard) care | no estimate extracted | 1 study · 299 participants | Ungraded |
Serious maternal morbidity Advance misoprostol distribution/provision to pregnant women for postpartum self‐administration vs usual (or standard) care | no estimate extracted | 1 study · 299 participants | Very low Downgraded: imprecision, indirectness |
Maternal death Advance misoprostol distribution/provision to pregnant women for postpartum self‐administration vs usual (or standard) care | no estimate extracted | 1 study · 299 participants | Very low Downgraded: imprecision, indirectness |
Blood transfusion Advance misoprostol distribution/provision to pregnant women for postpartum self‐administration vs usual (or standard) care | no estimate extracted | 1 study · 299 participants | Very low Downgraded: imprecision, indirectness |
Women not using/receiving misoprostol at birth Advance misoprostol distribution/provision to pregnant women for postpartum self‐administration vs usual (or standard) care | RR 0.5 [0.13, 1.95] | 1 study · 299 participants | Very low Downgraded: imprecision, indirectness |
Inappropriate use (or misuse) of misoprostol Advance misoprostol distribution/provision to pregnant women for postpartum self‐administration vs usual (or standard) care | RR 4.97 [0.24, 102.59] | 1 study · 299 participants | Very low Downgraded: imprecision, indirectness |
Maternal transfer or referral to a health facility Advance misoprostol distribution/provision to pregnant women for postpartum self‐administration vs usual (or standard) care | RR 0.66 [0.11, 3.91] | 1 study · 299 participants | Very low Downgraded: imprecision, indirectness |