Findings

What do systematic reviews say?

10 questions · 10 findings · 3 reviews

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No studies found 1 · 10%GRADE not reported 8 · 80%Very low 0 · 0%Low 0 · 0%Moderate 1 · 10%High 0 · 0%

Antifibrinolytic therapy - locally-applied tranexamic acid (TXA) mouthwash/solution (SoF eligibility: TXA or EACA; all included trials used topical TXA) vs Placebo mouthwash

Bleeding duration (minutes, all types of bleeding, minor and major) · People on continuous VKA treatment undergoing minor oral surgery or dental extractions (eligibility included DOACs and all ages; all four…

The review found no eligible studies for this question.

1 finding from 1 review

Antifibrinolytic therapy for preventing oral bleeding in people on anticoagulants undergoing minor oral surgery or… 2018 · Cochrane All outcomes
no estimate extracted
0 studies
No studies found

NMES vs no prophylaxis

Bleeding (major and minor) · participants at risk of venous thromboembolism

1 finding from 1 review

Neuromuscular electrical stimulation for the prevention of venous thromboembolism 2017 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 576 participants
GRADE not reported

NMES vs low‐dose heparin

Bleeding (major and minor) · participants at risk of venous thromboembolism

1 finding from 1 review

Neuromuscular electrical stimulation for the prevention of venous thromboembolism 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 194 participants
GRADE not reported

NMES vs Dextran 40

Bleeding (major and minor) · participants at risk of venous thromboembolism

1 finding from 1 review

Neuromuscular electrical stimulation for the prevention of venous thromboembolism 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 72 participants
GRADE not reported

Combined NMES and low‐dose heparin vs no prophylaxis

Bleeding (major and minor) · participants at risk of venous thromboembolism

1 finding from 1 review

Neuromuscular electrical stimulation for the prevention of venous thromboembolism 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 32 participants
GRADE not reported

Combined NMES and low‐dose heparin vs low‐dose heparin

Bleeding (major and minor) · participants at risk of venous thromboembolism

1 finding from 1 review

Neuromuscular electrical stimulation for the prevention of venous thromboembolism 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 31 participants
GRADE not reported

NMES vs GCS

Bleeding (major and minor) · participants at risk of venous thromboembolism

1 finding from 1 review

Neuromuscular electrical stimulation for the prevention of venous thromboembolism 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 36 participants
GRADE not reported

NMES vs IPCD

Bleeding (major and minor) · participants at risk of venous thromboembolism

1 finding from 1 review

Neuromuscular electrical stimulation for the prevention of venous thromboembolism 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 36 participants
GRADE not reported

NMES vs alternative prophylaxis

Bleeding (major and minor) · participants at risk of venous thromboembolism

1 finding from 1 review

Neuromuscular electrical stimulation for the prevention of venous thromboembolism 2017 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 415 participants
GRADE not reported

Low molecular weight heparin vs no prophylaxis

All adverse effects, including allergies at injection site, minor and major bleeding, others ( · adults undergoing KA

Low‐molecular‐weight heparin showed no clear difference in all adverse effects, including allergies at injection site, minor… compared with no prophylaxis (moderate certainty).

1 finding from 1 review

Interventions for preventing venous thromboembolism in adults undergoing knee arthroscopy 2022 · Cochrane Headline outcomes only
RR 1.85 [0.95, 3.59]
5 studies · 1978 participants
Moderate