Findings

What do systematic reviews say?

3 questions · 3 findings · 3 reviews · Breast Cancer

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 33.3%Moderate 1 · 33.3%High 1 · 33.3%

Anaemia (grade ≥ 3) · early triple‐negative breast cancer

Platinum‐containing chemotherapy probably leads to higher anaemia (grade III/IV) compared with chemotherapy without platinum (moderate certainty).

1 finding from 1 review

Platinum‐based chemotherapy for early triple‐negative breast cancer 2023 · Cochrane Headline outcomes only
RR 8.2 [5.66, 11.89]
19 studies · 4757 participants
Moderate

Anaemia grade 3 or 4 (safety population) by type of platinum agent in platinum regimen · women with metastatic breast cancer

The intervention leads to higher anaemia grade 3 or 4 (safety population) by type of platinum agent… (high certainty).

1 finding from 1 review

Platinum‐containing regimens for metastatic breast cancer 2017 · Cochrane Headline outcomes only
RR 1.72
7 studies · 1441 participants
High

Anaemia grade 3 or 4 (safety population) · women with metastatic triple‐negative breast cancer (mTNBC)

The intervention may leads to higher anaemia grade 3 or 4 (safety population) (low certainty).

1 finding from 1 review

Platinum‐containing regimens for triple‐negative metastatic breast cancer 2020 · Cochrane Headline outcomes only
RR 3.8
5 studies · 843 participants
Low