Findings

What do systematic reviews say?

4 questions · 4 findings · 3 reviews · Anaesthesia

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 50%Low 2 · 50%Moderate 0 · 0%High 0 · 0%

Intervention not reported

All‐cause mortality (within 30 days) · adults undergoing cardiac surgery under general anaesthesia

The intervention showed no clear difference in all‐cause mortality (within 30 days) (low certainty).

1 finding from 1 review

Perioperative beta‐blockers for preventing surgery‐related mortality and morbidity in adults undergoing cardiac surgery 2019 · Cochrane Headline outcomes only
RR 0.95 [0.47, 1.9]
29 studies · 4099 participants
Low

Perioperative beta‐blockers vs placebo or usual care

Early all‐cause mortality (within 30 days) · adults undergoing non‐cardiac surgery under general anaesthesia (to include: low‐risk, medium‐risk, and high‐risk surgeries)

Perioperative beta‐blockers showed no clear difference in early all‐cause mortality (within 30 days) compared with placebo or standard care (low certainty).

1 finding from 1 review

Perioperative beta‐blockers for preventing surgery‐related mortality and morbidity in adults undergoing non‐cardiac… 2019 · Cochrane Headline outcomes only
RR 1.17 [0.89, 1.54]
16 studies · 11446 participants
Low

Nitroglycerin vs no treatment

All‐cause mortality in 30 days post operation · patients (15 years of age and older) undergoing non‐cardiac surgery under any type of anaesthesia

It is very uncertain whether nitroglycerin changes all‐cause mortality in 30 days post operation compared with no treatment (very low certainty).

1 finding from 1 review

Nitrates for the prevention of cardiac morbidity and mortality in patients undergoing non‐cardiac surgery 2016 · Cochrane Headline outcomes only
RR 0.33 [0.01, 7.87]
1 study · 60 participants
Very low

Nitroglycerin vs placebo

All‐cause mortality in 30 days post operation · patients (15 years of age and older) undergoing non‐cardiac surgery under any type of anaesthesia

It is very uncertain whether nitroglycerin changes all‐cause mortality in 30 days post operation compared with placebo (very low certainty).

1 finding from 1 review

Nitrates for the prevention of cardiac morbidity and mortality in patients undergoing non‐cardiac surgery 2016 · Cochrane Headline outcomes only
RR 2.81 [0.12, 63.83]
2 studies · 89 participants
Very low