Findings

What do systematic reviews say?

4 questions · 4 findings · 4 reviews · Haematology

No studies found 1 · 25%GRADE not reported 0 · 0%Very low 1 · 25%Low 1 · 25%Moderate 1 · 25%High 0 · 0%

All‐cause mortality · patients with solid tumours without thrombocytopenia before chemotherapy

The intervention showed no clear difference in all‐cause mortality (low certainty).

1 finding from 1 review

All‐cause mortality · thrombocytopenia

Pathogen‐reduced platelets showed no clear difference in all‐cause mortality compared with standard platelets (moderate certainty).

1 finding from 1 review

Pathogen‐reduced platelets for the prevention of bleeding 2017 · Cochrane Headline outcomes only
RR 0.81 [0.5, 1.29]
6 studies · 1509 participants
Moderate

All‐cause mortality up to 30 days after the procedure · thrombocytopenia

The review found no eligible studies for this question.

1 finding from 1 review

All‐cause mortality · People with chronic bone marrow failure

It is very uncertain whether thrombopoietin mimetic changes all‐cause mortality compared with placebo (very low certainty).

1 finding from 1 review