Findings

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9 questions · 9 findings · 3 reviews

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No studies found 1 · 11.1%GRADE not reported 0 · 0%Very low 3 · 33.3%Low 3 · 33.3%Moderate 2 · 22.2%High 0 · 0%

Amiodarone vs other antiarrhythmics

All‐cause mortality · participants with high risk of sudden cardiac death (secondary prevention)

Amiodarone showed no clear difference in all‐cause mortality compared with other antiarrhythmics (low certainty).

1 finding from 1 review

Amiodarone versus other pharmacological interventions for prevention of sudden cardiac death 2015 · Cochrane Headline outcomes only
RR 1.03 [0.75, 1.42]
5 studies · 898 participants
Low

Amiodarone vs beta‐blocker

All‐cause mortality · participants with high risk of sudden cardiac death (secondary prevention)

It is very uncertain whether amiodarone changes all‐cause mortality compared with beta blockers (very low certainty).

1 finding from 1 review

Amiodarone versus other pharmacological interventions for prevention of sudden cardiac death 2015 · Cochrane Headline outcomes only
RR 0.96 [0.7, 1.32]
1 study · 189 participants
Very low

Amiodarone vs sotalol

All‐cause mortality · participants with high risk of sudden cardiac death (secondary prevention)

It is very uncertain whether amiodarone changes all‐cause mortality compared with sotalol (very low certainty).

1 finding from 1 review

Amiodarone versus other pharmacological interventions for prevention of sudden cardiac death 2015 · Cochrane Headline outcomes only
RR 1.08 [0.41, 2.83]
2 studies · 104 participants
Very low

Amiodarone vs placebo or no treatment

All‐cause mortality · participants with high risk of sudden cardiac death (primary prevention)

Amiodarone showed no clear difference in all‐cause mortality compared with placebo or no treatment (low certainty).

1 finding from 1 review

Amiodarone versus other pharmacological interventions for prevention of sudden cardiac death 2015 · Cochrane Headline outcomes only
RR 0.88 [0.78, 1]
17 studies · 8383 participants
Low

Amiodarone vs beta‐blocker

All‐cause mortality · beta blockers

Amiodarone may leads to lower all‐cause mortality compared with beta blockers (low certainty).

1 finding from 1 review

Amiodarone versus other pharmacological interventions for prevention of sudden cardiac death 2015 · Cochrane Headline outcomes only
RR 0.27 [0.1, 0.75]
2 studies · 342 participants
Low

Amiodarone vs other antiarrhythmics

All‐cause mortality · participants with high risk of sudden cardiac death (primary prevention)

Amiodarone probably leads to lower all‐cause mortality compared with other antiarrhythmics (moderate certainty).

1 finding from 1 review

Amiodarone versus other pharmacological interventions for prevention of sudden cardiac death 2015 · Cochrane Headline outcomes only
RR 0.37 [0.18, 0.76]
3 studies · 540 participants
Moderate

Amiodarone vs placebo or no treatment

All‐cause mortality · participants with high risk of sudden cardiac death (secondary prevention)

It is very uncertain whether amiodarone changes all‐cause mortality compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Amiodarone versus other pharmacological interventions for prevention of sudden cardiac death 2015 · Cochrane Headline outcomes only
RR 3.05 [1.33, 7.01]
2 studies · 440 participants
Very low

Amiodarone vs placebo or no treatment

All‐cause mortality · adults in sinus rhythm after cardioversion of atrial fibrillation

Amiodarone showed no clear difference in all‐cause mortality compared with placebo or no treatment (moderate certainty).

1 finding from 1 review

Antiarrhythmics for maintaining sinus rhythm after cardioversion of atrial fibrillation 2019 · Cochrane Headline outcomes only
RR 1.66 [0.55, 4.99]
2 studies · 444 participants
Moderate

Lidocaine vs amiodarone

All‐cause mortality · patients with myocardial infarction

The review found no eligible studies for this question.

1 finding from 1 review

Prophylactic lidocaine for myocardial infarction 2015 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found