Findings

What do systematic reviews say?

3 questions · 3 findings · 3 reviews · Headline outcomes only

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 3 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Antibiotics vs placebo or no intervention

Adverse events considered non‐serious · people with leptospirosis

It is very uncertain whether summary of findings table ‐ Antibiotics changes adverse events considered non‐serious compared with placebo or no intervention (very low certainty).

1 finding from 1 review

Antibiotics for treatment of leptospirosis 2024 · Cochrane Headline outcomes only
RR 1.05 [0.35, 3.17]
2 studies · 162 participants
Very low

Prostaglandin vs placebo or usual care

Adverse events considered non‐serious · adult patients after liver transplantation.

It is very uncertain whether prostaglandin changes adverse events considered non‐serious ( compared with placebo or standard care (very low certainty).

1 finding from 1 review

Prostaglandins for adult liver transplanted recipients 2023 · Cochrane Headline outcomes only
RR 1.19 [0.42, 3.36]
4 studies · 329 participants
Very low

Methylphenidate vs placebo or no intervention

Adverse events considered non‐serious (penicillin versus doxycycline) · Children and adolescents with ADHD

It is very uncertain whether methylphenidate changes proportion of participants with one or more adverse events… compared with placebo or no intervention (very low certainty).

1 finding from 1 review

Methylphenidate for children and adolescents with attention deficit hyperactivity disorder (ADHD) 2023 · Cochrane Headline outcomes only
RR 1.23 [1.11, 1.37]
35 studies · 5342 participants
Very low